M
Michael Schultz
Researcher at University of Otago
Publications - 127
Citations - 8205
Michael Schultz is an academic researcher from University of Otago. The author has contributed to research in topics: Inflammatory bowel disease & Colitis. The author has an hindex of 30, co-authored 119 publications receiving 7211 citations. Previous affiliations of Michael Schultz include University of Regensburg & Mercy Medical Center (Baltimore, Maryland).
Papers
More filters
Journal ArticleDOI
Sofosbuvir for previously untreated chronic hepatitis C infection
Eric Lawitz,Alessandra Mangia,David L. Wyles,Maribel Rodriguez-Torres,Tarek Hassanein,Stuart C. Gordon,Michael Schultz,M. Davis,Zeid Kayali,K. Rajender Reddy,Ira M. Jacobson,Kris V. Kowdley,L. Nyberg,G. Mani Subramanian,Robert H. Hyland,Sarah Arterburn,Deyuan Jiang,John McNally,Diana M. Brainard,William T. Symonds,John G. McHutchison,Aasim Sheikh,Zobair M. Younossi,Edward Gane +23 more
TL;DR: In a single-group study of sofosbuvir combined with peginterferon-ribavirin, patients with predominantly genotype 1 or 4 HCV infection had a rate of sustained virologic response of 90% at 12 weeks.
Journal ArticleDOI
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice.
Rance K. Sellon,Susan L. Tonkonogy,Michael Schultz,L. A. Dieleman,Wetonia B. Grenther,Ed Balish,Donna M. Rennick,Ryan Balfour Sartor +7 more
TL;DR: It is concluded that resident enteric bacteria are necessary for the development of spontaneous colitis and immune system activation in IL-10-deficient mice.
Journal ArticleDOI
Lactobacillus plantarum 299V in the treatment and prevention of spontaneous colitis in interleukin-10-deficient mice.
Michael Schultz,Claudia Veltkamp,L. A. Dieleman,Wetonia B. Grenther,Pricilla B. Wyrick,Susan L. Tonkonogy,R. Balfour Sartor +6 more
TL;DR: Results demonstrate that L. plantarum can attenuate immune-mediated colitis and suggest a potential therapeutic role for this agent in clinical inflammatory bowel diseases.
Journal ArticleDOI
Different subsets of enteric bacteria induce and perpetuate experimental colitis in rats and mice.
Heiko C. Rath,Michael Schultz,R Freitag,L. A. Dieleman,F. Li,H J Linde,J Schölmerich,Ryan Balfour Sartor +7 more
TL;DR: It is suggested that a subset of resident luminal bacteria induces colitis, but that a complex interaction of commensal aerobic and anaerobic bacteria provides the constant antigenic drive for chronic immune-mediated colonic inflammation.
Journal ArticleDOI
Lactobacillus GG in inducing and maintaining remission of Crohn's disease
Michael Schultz,Antje Timmer,Hans H Herfarth,R. Balfour Sartor,Jon A. Vanderhoof,Heiko C. Rath +5 more
TL;DR: This study could not demonstrate a benefit of L. GG in inducing or maintaining medically induced remission in CD, and the primary end point was sustained remission, defined as freedom from relapse at the 6 months follow-up visit.