M
Mieke M.E. Huijbers
Researcher at Wageningen University and Research Centre
Publications - 14
Citations - 720
Mieke M.E. Huijbers is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Thermus thermophilus & Proline dehydrogenase. The author has an hindex of 9, co-authored 14 publications receiving 544 citations. Previous affiliations of Mieke M.E. Huijbers include Delft University of Technology.
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Journal ArticleDOI
Flavin dependent monooxygenases.
Mieke M.E. Huijbers,S. Montersino,Adrie H. Westphal,Dirk Tischler,Dirk Tischler,Willem J. H. van Berkel +5 more
TL;DR: An update of the classification of flavin-dependent monooxygenases is presented and the latest advances in the understanding of their catalytic and structural properties are summarized.
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Light-Driven Enzymatic Decarboxylation of Fatty Acids.
TL;DR: Several fatty acids and their triglycerides are converted by CvFAP in near‐quantitative yield and exclusive selectivity upon illumination with blue light and very promising turnover numbers of up to 8000 were achieved in this proof‐of‐concept study.
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Hydrocarbon Synthesis via Photoenzymatic Decarboxylation of Carboxylic Acids.
Wuyuan Zhang,Ming Ma,Mieke M.E. Huijbers,Georgy A. Filonenko,Evgeny A. Pidko,Morten M. C. H. van Schie,Sabrina R. de Boer,Bastien O. Burek,Jonathan Z. Bloh,Willem J. H. van Berkel,Wilson A. Smith,Frank Hollmann +11 more
TL;DR: It is demonstrated that the decoy molecule approach enables conversion of a broad range of carboxylic acids by filling up the vacant substrate access channel of the photodecarboxylase.
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The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum')
Thomas Schafhauser,Norbert Kirchner,Andreas Kulik,Mieke M.E. Huijbers,Liane Flor,Thibault Caradec,David P. Fewer,Harald Gross,Philippe Jacques,Linda Jahn,Jouni Jokela,Valérie Leclère,Jutta Ludwig-Müller,Kaarina Sivonen,Willem J. H. van Berkel,Tilmann Weber,Wolfgang Wohlleben,Karl-Heinz van Pée +17 more
TL;DR: It is shown by RNA interference-mediated gene silencing that a nonribosomal peptide synthetase, CctN, is responsible for the synthesis of cyclochlorotine in Talaromyces islandicus, and a detailed model for cycloch chlorotine biosynthesis is proposed.
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Draft genome sequence of Talaromyces islandicus (« Penicillium islandicum ») WF-38-12, a neglected mold with significant biotechnological potential
Thomas Schafhauser,Daniel Wibberg,Christian Rückert,Anika Winkler,Liane Flor,Karl-Heinz van Pée,David P. Fewer,Kaarina Sivonen,Linda Jahn,Jutta Ludwig-Müller,Thibault Caradec,Philippe Jacques,Mieke M.E. Huijbers,Willem J. H. van Berkel,Tilmann Weber,Wolfgang Wohlleben,Jörn Kalinowski +16 more
TL;DR: The draft genome sequence of Talaromyces islandicus is reported, which provides the basis of a biotechnological usage of this species.