K
Kaarina Sivonen
Researcher at University of Helsinki
Publications - 280
Citations - 22399
Kaarina Sivonen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Microcystin & Anabaena. The author has an hindex of 76, co-authored 276 publications receiving 20453 citations. Previous affiliations of Kaarina Sivonen include University of Illinois at Urbana–Champaign & Meijo University.
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Journal ArticleDOI
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison,Mervyn J. Bibb,Gabriele Bierbaum,Albert A. Bowers,Tim S. Bugni,Grzegorz Bulaj,Julio A. Camarero,Dominic J. Campopiano,Gregory L. Challis,Jon Clardy,Paul D. Cotter,David J. Craik,Michael J. Dawson,Elke Dittmann,Stefano Donadio,Pieter C. Dorrestein,K. D. Entian,Michael A. Fischbach,John S. Garavelli,Ulf Göransson,Christian W. Gruber,Daniel H. Haft,Thomas Hemscheidt,Christian Hertweck,Colin Hill,Alexander R. Horswill,Marcel Jaspars,Wendy L. Kelly,Judith P. Klinman,Oscar P. Kuipers,A. James Link,Wen Liu,Mohamed A. Marahiel,Douglas A. Mitchell,Gert N. Moll,Bradley S. Moore,Rolf Müller,Satish K. Nair,Ingolf F. Nes,Gillian E. Norris,Baldomero M. Olivera,Hiroyasu Onaka,Mark L. Patchett,Joern Piel,Joern Piel,Martin J. T. Reaney,Sylvie Rebuffat,R. Paul Ross,Hans-Georg Sahl,Eric W. Schmidt,Michael E. Selsted,Konstantin Severinov,Ben Shen,Kaarina Sivonen,Leif Smith,Torsten Stein,Roderich D. Süssmuth,John R. Tagg,Gong-Li Tang,Andrew W. Truman,John C. Vederas,Christopher T. Walsh,Jonathan D. Walton,Silke C. Wenzel,Joanne M. Willey,Wilfred A. van der Donk +65 more
TL;DR: This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products.
Journal ArticleDOI
Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing
Patrick M. Shih,Patrick M. Shih,Dongying Wu,Amel Latifi,Seth D. Axen,David P. Fewer,Emmanuel Talla,Alexandra Calteau,Fei Cai,Nicole Tandeau de Marsac,Rosmarie Rippka,Michael Herdman,Kaarina Sivonen,Thérèse Coursin,Thierry Laurent,Lynne Goodwin,Matt Nolan,Karen W. Davenport,Cliff Han,Edward M. Rubin,Jonathan A. Eisen,Tanja Woyke,Muriel Gugger,Cheryl A. Kerfeld,Cheryl A. Kerfeld +24 more
TL;DR: This phylum-wide study highlights the benefits of diversity-driven genome sequencing, identifying more than 21,000 cyanobacterial proteins with no detectable similarity to known proteins, and foregrounds the diversity of light-harvesting proteins and gene clusters for secondary metabolite biosynthesis.
Journal ArticleDOI
Minimum Information about a Biosynthetic Gene cluster.
Marnix H. Medema,Marnix H. Medema,Renzo Kottmann,Pelin Yilmaz,Matthew Cummings,John B. Biggins,Kai Blin,Irene de Bruijn,Yit-Heng Chooi,Yit-Heng Chooi,Jan Claesen,R. Cameron Coates,Pablo Cruz-Morales,Srikanth Duddela,Stephanie Düsterhus,Daniel J. Edwards,David P. Fewer,Neha Garg,Christoph Geiger,Juan Pablo Gomez-Escribano,Anja Greule,Michalis Hadjithomas,Anthony S. Haines,Eric J. N. Helfrich,Matthew L. Hillwig,Keishi Ishida,Adam C. Jones,Carla S. Jones,Katrin Jungmann,Carsten Kegler,Hyun Uk Kim,Hyun Uk Kim,Peter Kötter,Daniel Krug,Joleen Masschelein,Alexey V. Melnik,Simone M. Mantovani,Emily A. Monroe,Marcus A. Moore,Nathan A. Moss,Hans-Wilhelm Nützmann,Guohui Pan,Amrita Pati,Daniel Petras,F. Jerry Reen,Federico Rosconi,Zhe Rui,Zhenhua Tian,Nicholas J. Tobias,Yuta Tsunematsu,Yuta Tsunematsu,Philipp Wiemann,Elizabeth E. Wyckoff,Xiaohui Yan,Grace Yim,Fengan Yu,Yunchang Xie,Bertrand Aigle,Alexander Kristian Apel,Carl J. Balibar,Emily P. Balskus,Francisco Barona-Gómez,Andreas Bechthold,Helge B. Bode,Rainer Borriss,Sean F. Brady,Axel A. Brakhage,Patrick Caffrey,Yi-Qiang Cheng,Jon Clardy,Russell J. Cox,Russell J. Cox,René De Mot,Stefano Donadio,Mohamed S. Donia,Wilfred A. van der Donk,Wilfred A. van der Donk,Pieter C. Dorrestein,Sean Doyle,Arnold J. M. Driessen,Monika Ehling-Schulz,K. D. Entian,Michael A. Fischbach,Lena Gerwick,William H. Gerwick,Harald Gross,Bertolt Gust,Christian Hertweck,Christian Hertweck,Monica Höfte,Susan E. Jensen,Jianhua Ju,Leonard Katz,Leonard Kaysser,Jonathan L. Klassen,Nancy P. Keller,Jan Kormanec,Oscar P. Kuipers,Tomohisa Kuzuyama,Nikos C. Kyrpides,Nikos C. Kyrpides,Hyung Jin Kwon,Sylvie Lautru,Rob Lavigne,Chia Y. Lee,Bai Linquan,Xinyu Liu,Wen Liu,Andriy Luzhetskyy,Taifo Mahmud,Yvonne Mast,Carmen Méndez,Mikko Metsä-Ketelä,Jason Micklefield,Douglas A. Mitchell,Bradley S. Moore,Leonilde M. Moreira,Rolf Müller,Brett A. Neilan,Markus Nett,Jens Nielsen,Jens Nielsen,Fergal O'Gara,Fergal O'Gara,Hideaki Oikawa,Anne Osbourn,Marcia S. Osburne,Bohdan Ostash,Shelley M. Payne,Jean-Luc Pernodet,Miroslav Petricek,Jörn Piel,Olivier Ploux,Jos M. Raaijmakers,José A. Salas,Esther K. Schmitt,Barry Scott,Ryan F. Seipke,Ben Shen,David H. Sherman,Kaarina Sivonen,Michael J. Smanski,Margherita Sosio,Evi Stegmann,Roderich D. Süssmuth,Kapil Tahlan,Christopher M. Thomas,Yi Tang,Andrew W. Truman,Muriel Viaud,Jonathan D. Walton,Christopher T. Walsh,Tilmann Weber,Gilles P. van Wezel,Barrie Wilkinson,Joanne M. Willey,Wolfgang Wohlleben,Gerard D. Wright,Nadine Ziemert,Changsheng Zhang,Sergey B. Zotchev,Rainer Breitling,Eriko Takano,Frank Oliver Glöckner,Frank Oliver Glöckner +164 more
TL;DR: This work proposes the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard, to facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters.
Journal ArticleDOI
Phylogenetic evidence for the early evolution of microcystin synthesis
Anne Rantala,David P. Fewer,Michael Hisbergues,Leo Rouhiainen,Jaana Vaitomaa,Thomas Börner,Kaarina Sivonen +6 more
TL;DR: The phylogenetic analyses indicate a coevolution of housekeeping genes and microcystin synthetase genes for the entire evolutionary history of the toxin, and strongly suggest that the genes encoding nodularin Synthetase are recently derived from those encoding microcysts.
Journal ArticleDOI
Effects of light, temperature, nitrate, orthophosphate, and bacteria on growth of and hepatotoxin production by Oscillatoria agardhii strains.
TL;DR: Two of the three toxic cultures studied produced more toxins in axenic than in nonaxenic cultures and higher concentrations had no additional effect.