M
Mikael Maksimow
Researcher at University of Turku
Publications - 13
Citations - 426
Mikael Maksimow is an academic researcher from University of Turku. The author has contributed to research in topics: Lymphatic system & Population. The author has an hindex of 6, co-authored 13 publications receiving 293 citations. Previous affiliations of Mikael Maksimow include Helsinki University Central Hospital.
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Journal ArticleDOI
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors
Ari Ahola-Olli,Peter Würtz,Aki S. Havulinna,Kristiina Aalto,Niina Pitkänen,Terho Lehtimäki,Mika Kähönen,Leo-Pekka Lyytikäinen,Emma Raitoharju,Ilkka Seppälä,Antti-Pekka Sarin,Samuli Ripatti,A. Palotie,Markus Perola,Jorma S. A. Viikari,Jorma S. A. Viikari,Sirpa Jalkanen,Mikael Maksimow,Veikko Salomaa,Marko Salmi,Johannes Kettunen,Olli T. Raitakari,Olli T. Raitakari,Olli T. Raitakari +23 more
TL;DR: In this paper, the causal roles of cytokine signaling and upstream inflammation in immune-related and other chronic diseases were clarified using a genome-wide association study (GWAS) of up to 8,293 Finns.
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Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages.
TL;DR: The authors found that stabilin-1/CLEVER-1 was involved in the scavenging of Ac-LDL (acetylated low density lipoprotein) and in the uptake of fluorescently labeled model antigen OVA.
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Early prediction of persistent organ failure by soluble CD73 in patients with acute pancreatitis
Mikael Maksimow,Lea Kyhälä,Anne Nieminen,Leena Kylänpää,Kristiina Aalto,Kati Elima,Panu Mentula,Mari S. Lehti,Pauli Puolakkainen,Gennady G. Yegutkin,Sirpa Jalkanen,Sirpa Jalkanen,Heikki Repo,Marko Salmi,Marko Salmi +14 more
TL;DR: In this paper, new biomarkers are needed to better predict the severity of acute pancreatitis, and CD73/ecto-5'nucleotidase is an enzyme that generates adenosine, which dampens inflammation and improves vascular barrier function.
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The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease
Marita Kalaoja,Laura J Corbin,Vanessa Y Tan,Ari Ahola-Olli,Ari Ahola-Olli,Aki S. Havulinna,Kristiina Santalahti,Niina Pitkänen,Terho Lehtimäki,Leo-Pekka Lyytikäinen,Emma Raitoharju,Ilkka Seppälä,Mika Kähönen,Samuli Ripatti,Samuli Ripatti,Aarno Palotie,Markus Perola,Markus Perola,Jorma S. A. Viikari,Jorma S. A. Viikari,Sirpa Jalkanen,Mikael Maksimow,Veikko Salomaa,Marko Salmi,Olli T. Raitakari,Olli T. Raitakari,Johannes Kettunen,Johannes Kettunen,Nicholas J. Timpson +28 more
TL;DR: In this article, the role of cytokines as intermediates in the pathway from increased adiposity to disease was investigated, and the impact of BMI-driven cytokines on risk of obesityrelated diseases was investigated.
Journal ArticleDOI
Plasma levels of hepatocyte growth factor and placental growth factor predict mortality in a general population: a prospective cohort study.
Kristiina Santalahti,Aki S. Havulinna,Mikael Maksimow,Tanja Zeller,Stefan Blankenberg,Aki Vehtari,Heikki Joensuu,Sirpa Jalkanen,Veikko Salomaa,Marko Salmi +9 more
TL;DR: In this article, the authors measured the levels of a range of growth factors involved in leucocyte production and angiogenesis and used them as predictors of risk for all-cause cardiovascular disease (CVD) or cancer mortality.