M
Mikhail I. Shtilman
Researcher at D. Mendeleev University of Chemical Technology of Russia
Publications - 52
Citations - 936
Mikhail I. Shtilman is an academic researcher from D. Mendeleev University of Chemical Technology of Russia. The author has contributed to research in topics: Polymerization & Drug delivery. The author has an hindex of 12, co-authored 45 publications receiving 722 citations. Previous affiliations of Mikhail I. Shtilman include Bauman Moscow State Technical University.
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Journal ArticleDOI
Amphiphilic vinyl polymers effectively prolong liposome circulation time in vivo
Vladimir P. Torchilin,Mikhail I. Shtilman,Vladimir S. Trubetskoy,Kathleen R. Whiteman,Alexander M. Milstein +4 more
TL;DR: Newly synthesized amphiphilic polyacrylamide and poly(vinyl pyrrolidone), single terminus-modified with long-chain fatty acyl groups, are able to incorporate into the liposomal membrane, and similar to poly(ethylene glycol) prolong liposomes circulation in vivo and decrease liposome accumulation in the liver.
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Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system
Ayse Basak Engin,Dragana Nikitovic,Monica Neagu,Petra Henrich-Noack,Anca Oana Docea,Mikhail I. Shtilman,Kirill S. Golokhvast,Aristidis Tsatsakis,Aristidis Tsatsakis +8 more
TL;DR: This review critically discusses the specific behavior of NPs that are within the ECM domain, and passing through the biological barriers, and regenerative and toxicological aspects of nanomaterials are debated in terms of the immune cells-NPs interactions.
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Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics
Zoi Piperigkou,Konstantina Karamanou,Ayse Basak Engin,Chrysostomi Gialeli,Anca Oana Docea,Demitrios H. Vynios,Mauro S. G. Pavão,Kirill S. Golokhvast,Mikhail I. Shtilman,Athanassios Argiris,Ekaterina I. Shishatskaya,Aristidis Tsatsakis +11 more
TL;DR: It is discussed that exposure to nanostructures incorporated to polymer composites, may result in potential human health risks, and expanding the knowledge of nanoparticle toxicity will facilitate designing of safer nanocomposites and their application in a beneficial manner.
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Nanosized carriers based on amphiphilic poly-N-vinyl-2-pyrrolidone for intranuclear drug delivery.
Anna L. Luss,Pavel P. Kulikov,Sven Buskov Romme,Camilla L. Andersen,Cristian Pablo Pennisi,Anca Oana Docea,A. N. Kuskov,Kelly Velonia,Yaroslav Mezhuev,Mikhail I. Shtilman,Aristidis Tsatsakis,Leonid Gurevich +11 more
TL;DR: This finding opens an intriguing possibility of intranuclear delivery by merely tailoring the size of polymeric carriers, thus promising a new approach for cancer therapies.
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Amphiphilic poly-N-vinylpyrrolidone nanoparticles as carriers for non-steroidal, anti-inflammatory drugs: In vitro cytotoxicity and in vivo acute toxicity study.
A. N. Kuskov,Pavel P. Kulikov,Anastasia V. Goryachaya,Manolis Tzatzarakis,Anca Oana Docea,Kelly Velonia,Mikhail I. Shtilman,Aristidis Tsatsakis +7 more
TL;DR: These novel amphiphilic poly-N-vinylpyrrolidone nanoparticles can be considered as potential carriers for new, highly efficient, injectable drug delivery systems for hydrophobic drugs such as indomethacin.