M
Milton Rocha Moraes
Researcher at Universidade Católica de Brasília
Publications - 75
Citations - 1760
Milton Rocha Moraes is an academic researcher from Universidade Católica de Brasília. The author has contributed to research in topics: Blood pressure & Aerobic exercise. The author has an hindex of 20, co-authored 73 publications receiving 1494 citations. Previous affiliations of Milton Rocha Moraes include University of São Paulo & Federal University of São Paulo.
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Journal ArticleDOI
Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.
Carla Giordano,Luisa Iommarini,Luca Giordano,Alessandra Maresca,Annalinda Pisano,Maria Lucia Valentino,Leonardo Caporali,Rocco Liguori,Stefania Deceglie,Marina Roberti,Francesca Fanelli,Flavio Fracasso,Fred N. Ross-Cisneros,Pio D'Adamo,Gavin Hudson,Angela Pyle,Patrick Yu-Wai-Man,Patrick F. Chinnery,Massimo Zeviani,Solange Rios Salomão,Adriana Berezovsky,Rubens Belfort,Dora Fix Ventura,Milton Rocha Moraes,Milton Moraes Filho,Piero Barboni,Federico Sadun,Annamaria De Negri,Alfredo A. Sadun,Andrea Tancredi,Massimiliano Mancini,Giulia d'Amati,Paola Loguercio Polosa,Palmiro Cantatore,Valerio Carelli +34 more
TL;DR: Giordano et al. show that mitochondrial DNA content and mitochondrial mass are both increased in tissues and cells from unaffected mutation carriers relative to affected relatives and control individuals, suggesting upregulation of mitochondrial biogenesis may represent a therapeutic target.
Journal ArticleDOI
Extensive investigation of a large Brazilian pedigree of 11778/haplogroup J Leber hereditary optic neuropathy.
Alfredo A. Sadun,Valerio Carelli,Valerio Carelli,Solange Rios Salomão,Solange Rios Salomão,Adriana Berezovsky,Peter A. Quiros,Federico Sadun,A.M. DeNegri,Rafael E. Andrade,Milton Rocha Moraes,Angelo Passos,Patrícia K. Kjaer,Josenilson Martins Pereira,Maria Lucia Valentino,Stan Schein,Rubens Belfort +16 more
TL;DR: The initial results indicate the strong influence of environmental risk factors on a newly identified pedigree with Leber hereditary optic neuropathy, and further genetic analysis may reveal a role for the nuclear genome.
Journal ArticleDOI
Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.
Carlos Castilho Barros,Anderson Sola Haro,Fernanda Jacqueline Russo,Ines Schadock,Sandro Soares de Almeida,Rosane Aparecida Ribeiro,Emerielle C. Vanzela,Valéria P. Lanzoni,Flavio C. Barros,Milton Rocha Moraes,Marcelo A. Mori,Reury Frank Pereira Bacurau,Martin Würtele,Antonio C. Boschero,Everardo M. Carneiro,Michael Bader,João Bosco Pesquero,Ronaldo C. Araujo +17 more
TL;DR: It is concluded that kinin receptors are important for modulation of insulin secretion and for the preservation of normal glucose levels and hepatic functions in obese mice, suggesting a protective role of the KKS regarding complications associated with obesity and T2DM.
Journal ArticleDOI
Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers.
Milton Rocha Moraes,Reury Frank Pereira Bacurau,João Daivison Silva Ramalho,Felipe C.G. Reis,Dulce Elena Casarini,Jair R. Chagas,Vitor Oliveira,Elisa Mieko Suemitsu Higa,Dulcinéia Saes Parra Abdalla,Jorge L. Pesquero,João Bosco Pesquero,Ronaldo C. Araujo +11 more
TL;DR: Investigation of the involvement of the vasodilators bradykinin and des-Arg9-BK and kallikrein activity in post-exercise hypotension promoted by 35 min of cycle ergometer (CE) or circuit weight-training (CWT) bouts in normotensive and hypertensive individuals suggests that the kallIKrein-kinin system may be involved in post.
Journal ArticleDOI
Effect of 12 weeks of resistance exercise on post-exercise hypotension in stage 1 hypertensive individuals
Milton Rocha Moraes,Reury Frank Pereira Bacurau,Herbert Gustavo Simões,Carmen Silvia Grubert Campbell,M A Pudo,Frederick Wasinski,João Bosco Pesquero,Martin Würtele,Ronaldo C. Araujo +8 more
TL;DR: The data demonstrate that PEH, following an acute exercise session, can indeed be attenuated after 12 weeks of training in hypertensive stage 1 patients not using antihypertensive medication.