Ming Yuan Li

TL;DR: The newly developed ppNT assay does not require Biosafety Level 3 containment and is thus a relatively high-throughput assay, well suited for large-scale seroepidemiology studies which are needed to better understand the ecology and epidemiology of MERS-CoV.

TL;DR: In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep, goats, cattle, cattle and chickens, but dromedary camels had a high prevalence of MERS- coV antibodies.

TL;DR: The findings shed new light on a molecular mechanism used by dengue viruses during the late stages of the life cycle and demonstrate a novel function for class II Arf proteins.

TL;DR: This study demonstrates that dengue virus (DENV) interacts with KDEL receptors (KDELR), which cycle between the ER and Golgi apparatus, for vesicular transport from ER to Golgi, and uncovers a function for KDELR as an internal receptor involved in DENV trafficking.

TL;DR: These findings place KDLER at the center of a complex system of signals, which originate at the Golgi but exert their effects at multiple levels, including cell invasion and virus infection.