Minggang Chen

TL;DR: A functional glutamatergic circuit that mediates noncanonical excitatory interactions in the retina and probably plays a role in generating ON-OFF responses, crossover excitation, and lateral excitation is revealed.

TL;DR: Ca(2+)-dependent co-release of a new combination of inhibitory and excitatory neurotransmitters, namely, glycine and glutamate, by the vGluT3-expressing amacrine cell (GAC) in the mouse retina suggests a unique advantage in differential detection of visual field uniformity and contrast.

TL;DR: In this article, a mouse early postnatal direction-selective ganglion cells (DSGCs) exhibited a clear selectivity for the direction of motion at the onset of light sensitivity, and the degree of direction selectivity was not affected by rearing in complete darkness from birth to postnatal day 11 or 30.

TL;DR: Findings help to simplify models of direction selectivity by ruling out complex computation at BC terminals and show that CB5 comprises two functional subclasses of BCs, which are not directionally selective.

TL;DR: It is suggested that propagating patterns of spontaneous retinal waves are essential for normal development of the retinotopic map, even while overall activity levels are significantly reduced, and support an instructive role for spontaneousretinal activity in both eye‐specific segregation and retinOTopic refinement.