M
Mircea Alexandru Mateescu
Researcher at Université du Québec à Montréal
Publications - 97
Citations - 2284
Mircea Alexandru Mateescu is an academic researcher from Université du Québec à Montréal. The author has contributed to research in topics: Diamine oxidase & Controlled release. The author has an hindex of 26, co-authored 90 publications receiving 2013 citations.
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Journal ArticleDOI
A Novel Cross‐linked Poly(vinyl alcohol) (PVA) for Vascular Grafts
Marc Chaouat,Catherine Le Visage,Wilms Emmanuel Baille,Brigitte Escoubet,Frédéric Chaubet,Frédéric Chaubet,Mircea Alexandru Mateescu,Didier Letourneur +7 more
TL;DR: In this paper, a simple process for PVA cross-linking with sodium trimetaphosphate to form membrane devices suitable for biomedical applications was proposed, which requires no organic solvent, nor melting process to obtain films with high mechanical strength.
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Controlled release of theophylline from cross-linked amylose tablets
TL;DR: The analysis of the data indicates that an anomalous release mechanism controls the transport of the drug; this includes neither Fickian diffusion nor glassy/rubbery transition.
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Cross-linked high amylose starch derivatives as matrices for controlled release of high drug loadings.
TL;DR: These new polymeric excipients are able to control the release over 20 h from monolithic tablets loaded with 20 to 60% drug and represent a novel generation of pharmaceuticalexcipients recommended for high loading dosage formulations.
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Structure-properties relationship in cross-linked high-amylose starch for use in controlled drug release
TL;DR: Best release properties and highest mechanical hardness were obtained from CLHAS matrices with low-to-moderate crystallinity, where the V- and the B-type structures coexist with amorphous regions.
Journal ArticleDOI
Cross-linked amylose as matrix for drug controlled release. X-ray and FT-IR structural analysis
Yves Dumoulin,Yves Dumoulin,Serge Alex,Pompilia Ispas Szabo,Louis Cartilier,Mircea Alexandru Mateescu +5 more
TL;DR: For cross-linked amylose (CLA) tablets prepared by direct compression, a linear increase in cross-linking degree (cld) defined as percentage of epichlorohydrin cross-linker/polymer, generates non-monotonous variation of drug release time.