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Mirjana Mihailović

Researcher at University of Belgrade

Publications -  86
Citations -  1144

Mirjana Mihailović is an academic researcher from University of Belgrade. The author has contributed to research in topics: Oxidative stress & Diabetes mellitus. The author has an hindex of 17, co-authored 81 publications receiving 923 citations. Previous affiliations of Mirjana Mihailović include University of Kragujevac & Laboratory of Molecular Biology.

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In vitro antioxidant activity of selected 4-hydroxy-chromene-2-one derivatives-SAR, QSAR and DFT studies.

TL;DR: Bond dissociation enthalpies of coumarin 4-OH, Natural Bond Orbital (NBO) gained hybridization of the oxygen, acidity of the hydrogen atom and various molecular descriptors obtained, were correlated with biological activity, after which 20 new antioxidant structures were designed, using the most favorable structural motifs, with much improved predicted activity in vitro.
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Methanol extract from the stem of Cotinus coggygria Scop., and its major bioactive phytochemical constituent myricetin modulate pyrogallol-induced DNA damage and liver injury.

TL;DR: The results suggest that pro-surviving Akt activity and STAT3 protein expression play important roles in decreasing DNA damage and in mediating hepatic protection by the methanol extract of C. coggygria against pyrogallol-induced toxicity.
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Antioxidative effects of phenolic extracts from chestnut leaves, catkins and spiny burs in streptozotocin-treated rat pancreatic β-cells

TL;DR: It was concluded that chestnut extracts increased cell viability after STZ treatment as a result of their antioxidative properties.
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Alpha-lipoic acid upregulates antioxidant enzyme gene expression and enzymatic activity in diabetic rat kidneys through an O-GlcNAc-dependent mechanism.

TL;DR: α-Lipoic acid administration activates a coordinated cytoprotective response against diabetes-induced oxidative injury in kidney tissue through an O-GlcNAc-dependent mechanism.