Milan Mladenović

TL;DR: The most famous representative of the class, tylosin A, as well as some derivatives of desmycosin (tylosin B), have shown antimalarial activity, and this provides the opportunity to investigate these drugs as cheap and effective antimalarials.

TL;DR: It could be concluded that the use of G. asclepiadea extracts in the treatment of chemical-induced hepatotoxicity is safe and effective.

TL;DR: Bond dissociation enthalpies of coumarin 4-OH, Natural Bond Orbital (NBO) gained hybridization of the oxygen, acidity of the hydrogen atom and various molecular descriptors obtained, were correlated with biological activity, after which 20 new antioxidant structures were designed, using the most favorable structural motifs, with much improved predicted activity in vitro.

TL;DR: The results suggest that pro-surviving Akt activity and STAT3 protein expression play important roles in decreasing DNA damage and in mediating hepatic protection by the methanol extract of C. coggygria against pyrogallol-induced toxicity.

TL;DR: Tested extracts, rich in polyphenolic compounds, attenuate cisplatin-induced liver and kidney oxidative stress, reduce tissue damage, and enhance the antioxidative status of experimental animals during cisPlatin application.