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Sanja Matić

Researcher at University of Kragujevac

Publications -  58
Citations -  859

Sanja Matić is an academic researcher from University of Kragujevac. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 14, co-authored 47 publications receiving 607 citations.

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In vitro antioxidant activity of selected 4-hydroxy-chromene-2-one derivatives-SAR, QSAR and DFT studies.

TL;DR: Bond dissociation enthalpies of coumarin 4-OH, Natural Bond Orbital (NBO) gained hybridization of the oxygen, acidity of the hydrogen atom and various molecular descriptors obtained, were correlated with biological activity, after which 20 new antioxidant structures were designed, using the most favorable structural motifs, with much improved predicted activity in vitro.
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Methanol extract from the stem of Cotinus coggygria Scop., and its major bioactive phytochemical constituent myricetin modulate pyrogallol-induced DNA damage and liver injury.

TL;DR: The results suggest that pro-surviving Akt activity and STAT3 protein expression play important roles in decreasing DNA damage and in mediating hepatic protection by the methanol extract of C. coggygria against pyrogallol-induced toxicity.
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Filipendula ulmaria extracts attenuate cisplatin-induced liver and kidney oxidative stress in rats: In vivo investigation and LC-MS analysis.

TL;DR: Tested extracts, rich in polyphenolic compounds, attenuate cisplatin-induced liver and kidney oxidative stress, reduce tissue damage, and enhance the antioxidative status of experimental animals during cisPlatin application.