M
Mitsuo Sekine
Researcher at National Institute of Technology and Evaluation
Publications - 18
Citations - 3481
Mitsuo Sekine is an academic researcher from National Institute of Technology and Evaluation. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 14, co-authored 18 publications receiving 3311 citations.
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Journal ArticleDOI
Complete sequencing and characterization of 21,243 full-length human cDNAs
Toshio Ota,Yutaka Suzuki,Tetsuo Nishikawa,Tetsuji Otsuki,Tomoyasu Sugiyama,Ryotaro Irie,Ai Wakamatsu,Koji Hayashi,Hiroyuki Sato,Keiichi Nagai,Kouichi Kimura,Hiroshi Makita,Mitsuo Sekine,Masaya Obayashi,Tatsunari Nishi,Toshikazu Shibahara,Toshihiro Tanaka,Shizuko Ishii,Junichi Yamamoto,Kaoru Saito,Yuri Kawai,Yuko Isono,Yoshitaka Nakamura,Kenji Nagahari,Katsuhiko Murakami,Tomohiro Yasuda,Takao Iwayanagi,Masako Wagatsuma,Akiko Shiratori,Hiroaki Sudo,Takehiko Hosoiri,Yoshiko Kaku,Hiroyo Kodaira,Hiroshi Kondo,Masanori Sugawara,Makiko Takahashi,Katsuhiro Kanda,Takahide Yokoi,Takako Furuya,Emiko Kikkawa,Yuhi Omura,Kumi Abe,Kumiko Kamihara,Naoko Katsuta,Kazuomi Sato,Machiko Tanikawa,Makoto Yamazaki,Ken Ninomiya,Tadashi Ishibashi,Hiromichi Yamashita,Katsuji Murakawa,Kiyoshi Fujimori,Hiroyuki Tanai,Manabu Kimata,Motoji Watanabe,Susumu Hiraoka,Yoshiyuki Chiba,Shinichi Ishida,Yukio Ono,Sumiyo Takiguchi,Susumu Watanabe,Makoto Yosida,Tomoko Hotuta,Junko Kusano,Keiichi Kanehori,Asako Takahashi-Fujii,Hiroto Hara,Tomo-o Tanase,Yoshiko Nomura,Sakae Togiya,Fukuyo Komai,Reiko Hara,Kazuha Takeuchi,Miho Arita,Nobuyuki Imose,Kaoru Musashino,Hisatsugu Yuuki,Atsushi Oshima,Naokazu Sasaki,Satoshi Aotsuka,Yoko Yoshikawa,Hiroshi Matsunawa,Tatsuo Ichihara,Namiko Shiohata,Sanae Sano,Shogo Moriya,Hiroko Momiyama,Noriko Satoh,Sachiko Takami,Yuko Terashima,Osamu Suzuki,Satoshi Nakagawa,Akihiro Senoh,Hiroshi Mizoguchi,Yoshihiro Goto,Fumio Shimizu,Hirokazu Wakebe,Haretsugu Hishigaki,Takeshi Watanabe,Akio Sugiyama,Makoto Takemoto,Bunsei Kawakami,Masaaki Yamazaki,Koji Watanabe,Ayako Kumagai,Shoko Itakura,Yasuhito Fukuzumi,Yoshifumi Fujimori,Megumi Komiyama,Hiroyuki Tashiro,Akira Tanigami,Tsutomu Fujiwara,Toshihide Ono,Katsue Yamada,Yuka Fujii,Kouichi Ozaki,Maasa Hirao,Yoshihiro Ohmori,Ayako Kawabata,Takeshi Hikiji,Naoko Kobatake,Hiromi Inagaki,Yasuko Ikema,Sachiko Okamoto,Rie Okitani,Takuma Kawakami,Saori Noguchi,Tomoko Itoh,Keiko Shigeta,Tadashi Senba,Kyoka Matsumura,Yoshie Nakajima,Takae Mizuno,Misato Morinaga,Masahide Sasaki,Takushi Togashi,Masaaki Oyama,Hiroko Hata,Manabu Watanabe,Takami Komatsu,Junko Mizushima-Sugano,Tadashi Satoh,Tadashi Satoh,Yuko Shirai,Yukiko Takahashi,Kiyomi Nakagawa,Koji Okumura,Takahiro Nagase,Nobuo Nomura,Hisashi Kikuchi,Yasuhiko Masuho,Riu Yamashita,Kenta Nakai,Tetsushi Yada,Yusuke Nakamura,Osamu Ohara,Takao Isogai,Sumio Sugano,Sumio Sugano +158 more
TL;DR: There seems to be a slight bias against GC-rich transcripts in current gene prediction procedures in the “full-length long Japan” collection of sequenced human cDNAs.
Journal ArticleDOI
Complete Sequence and Gene Organization of the Genome of a Hyper-thermophilic Archaebacterium, Pyrococcus horikoshii OT3
Yutaka Kawarabayasi,Mituhiro Sawada,Hiroshi Horikawa,Yuji Haikawa,Yumi Hino,Saori Yamamoto,Mitsuo Sekine,Sin-ichi Baba,Hiroki Kosugi,Akira Hosoyama,Yoshimi Nagai,Mari Sakai,Keiko Ogura,Rie Otsuka,Hidekazu Nakazawa,Minako Takamiya,Yuhko Ohfuku,Tomomichi Funahashi,Toshihiro Tanaka,Yutaka Kudoh,Jun Yamazaki,Norihiro Kushida,Akio Oguchi,Ken-ichi Aoki,Takio Yoshizawa,Yoshinobu Nakamura,Frank T. Robb,Koki Horikoshi,Yaeko Masuchi,Hiroaki Shizuya,Hisasi Kikuchi +30 more
TL;DR: The complete sequence of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3, has been determined by assembling the sequences of the physical map-based contigs of fosmid clones and of long polymerase chain reaction (PCR) products which were used for gap-filling.
Journal ArticleDOI
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura,Ai Wakamatsu,Yutaka Suzuki,Toshio Ota,Tetsuo Nishikawa,Riu Yamashita,Junichi Yamamoto,Mitsuo Sekine,Katsuki Tsuritani,Hiroyuki Wakaguri,Shizuko Ishii,Tomoyasu Sugiyama,Kaoru Saito,Yuko Isono,Ryotaro Irie,Norihiro Kushida,Takahiro Yoneyama,Rie Otsuka,Katsuhiro Kanda,Takahide Yokoi,Hiroshi Kondo,Masako Wagatsuma,Katsuji Murakawa,Shinichi Ishida,Tadashi Ishibashi,Asako Takahashi-Fujii,Tomo-o Tanase,Keiichi Nagai,Hisashi Kikuchi,Kenta Nakai,Takao Isogai,Sumio Sugano +31 more
TL;DR: The findings suggest that use of alternate promoters and consequent alternative use of first exons should play a pivotal role in generating the complexity required for the highly elaborated molecular systems in humans.
Journal ArticleDOI
Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1.
Yutaka Kawarabayasi,Yumi Hino,Hirosh Horikawa,Syuji Yamazaki,Yuji Haikawa,Koji Jin-no,Mikio Takahashi,Mitsuo Sekine,Sin-ichi Baba,Akiho Ankai,Hiroki Kosugi,Akira Hosoyama,Shigehiro Fukui,Yoshimi Nagai,Keiko Nishijima,Hidekazu Nakazawa,Minako Takamiya,Sayaka Masuda,Tomomichi Funahashi,Toshihiro Tanaka,Yutaka Kudoh,Jun Yamazaki,Norihiro Kushida,Akio Oguchi,Ken-ichi Aoki,Kenji Kubota,Yoshinobu Nakamura,Norimichi Nomura,Yoshihiko Sako,Hisasi Kikuchi +29 more
TL;DR: The complete sequence of the genome of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1, which optimally grows at 95 degrees C, has been determined by the whole genome shotgun method with some modifications.
Journal ArticleDOI
Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7.
Yutaka Kawarabayasi,Yumi Hino,Hiroshi Horikawa,Koji Jin-no,Mikio Takahashi,Mitsuo Sekine,Sin-ichi Baba,Akiho Ankai,Hiroki Kosugi,Akira Hosoyama,Shigehiro Fukui,Yoshimi Nagai,Keiko Nishijima,Rie Otsuka,Hidekazu Nakazawa,Minako Takamiya,Yumiko Kato,Takio Yoshizawa,Toshihiro Tanaka,Yutaka Kudoh,Jun Yamazaki,Norihiro Kushida,Akio Oguchi,Ken-ichi Aoki,Sayaka Masuda,Masao Yanagii,Masami Nishimura,Akihiko Yamagishi,Tairo Oshima,Hisasi Kikuchi +29 more
TL;DR: Sequence comparison provided evidence suggesting the integration of plasmid, rearrangement of genomic structure, and duplication of genomic regions that may be responsible for the larger genomic size of the S. tokodaii strain7 genome.