M
Mónica Garzón
Researcher at Laboratory of Molecular Biology
Publications - 9
Citations - 409
Mónica Garzón is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 5, co-authored 9 publications receiving 295 citations.
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Journal ArticleDOI
Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer.
Kirstine Jacobsen,Jordi Bertran-Alamillo,Miguel Angel Molina,Cristina Teixidó,Niki Karachaliou,Martin Haar Pedersen,Josep Castellví,Mónica Garzón,Carles Codony-Servat,Jordi Codony-Servat,Ana Giménez-Capitán,Ana Drozdowskyj,Santiago Viteri,Martin R. Larsen,Ulrik Lassen,Enriqueta Felip,Trever G. Bivona,Henrik J. Ditzel,Henrik J. Ditzel,Rafael Rosell +19 more
TL;DR: It is shown that resistant tumors display high Akt activation and that a combined treatment with AKT inhibitors causes synergistic tumour growth inhibition in vitro and in vivo.
Journal ArticleDOI
Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients
Umberto Malapelle,Clara Mayo de-las-Casas,Danilo Rocco,Mónica Garzón,Pasquale Pisapia,Núria Jordana-Ariza,Maria Giovanna Russo,Roberta Sgariglia,Caterina De Luca,Francesco Pepe,Alejandro Martinez-Bueno,Daniela Morales-Espinosa,Maria Gonzalez-Cao,Niki Karachaliou,Santiago Viteri Ramirez,Claudio Bellevicine,Miguel Angel Molina-Vila,Rafael Rosell,Giancarlo Troncone +18 more
TL;DR: A panel to use in ultra-deep sequencing to identify mutated alleles in cfDNA involved in non-small-cell lung cancer, gastrointestinal stromal tumour, colorectal carcinoma and melanoma and a feasible NGS panel for cfDNA analysis in clinical practice is developed.
Journal ArticleDOI
Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection: The Phase 2 DURVAST Study
Maria Gonzalez-Cao,Teresa Moran,Judith Dalmau,Javier Garcia-Corbacho,Jillian Wilhelmina Paulina Bracht,R. Bernabé,Oscar Juan,Javier de Castro,R. Blanco,Ana Drozdowskyj,Jordi Argilaguet,Andreas Meyerhans,Andreas Meyerhans,Julià Blanco,Julia G. Prado,Jorge Carrillo,Bonaventura Clotet,Bartomeu Massuti,Mariano Provencio,Miguel Angel Molina-Vila,Clara Mayo de las Casa,Mónica Garzón,Peng Cao,Chung-Ying Huang,Javier Martinez-Picado,Rafael Rosell +25 more
TL;DR: Durvalumab treatment was feasible and safe in HIV-1-infected patients with cancer receiving combination antiretroviral therapy and patients on suppressive antifiltration therapy with advanced cancer should have access to cancer immunotherapy treatments.
Journal ArticleDOI
Liquid Biopsy in Non-Small Cell Lung Cancer
Miguel Angel Molina-Vila,Clara Mayo-de-las-Casas,Ana Giménez-Capitán,Núria Jordana-Ariza,Mónica Garzón,Ariadna Balada,Sergi Villatoro,Cristina Teixidó,Beatriz García-Peláez,Cristina Aguado,Maria José Catalán,Raquel Campos,Ana Pérez-Rosado,Jordi Bertran-Alamillo,Alejandro Martinez-Bueno,Maria-de-los-Llanos Gil,Maria Gonzalez-Cao,Xavier Gonzalez,Daniela Morales-Espinosa,Santiago Viteri,Niki Karachaliou,Rafael Rosell +21 more
TL;DR: The techniques available for the isolation and analysis of circulating free DNA and RNA, exosomes, tumor-educated platelets, and circulating tumor cells from the blood of cancer patients are summarized, and the clinical applications of liquid biopsy testing in lung cancer are discussed.
Journal ArticleDOI
Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection
Maria Gonzalez-Cao,Teresa Moran,Judith Dalmau,Javier Garcia-Corbacho,Jillian Wilhelmina Paulina Bracht,Reyes Bernabe Caro,O. Juan-Vidal,Javier de Castro,R. Blanco,Ana Drozdowskyj,Jordi Argilaguet,Andreas Meyerhans,Julià Blanco,Julia G. Prado,Jorge Carrillo,Bonaventura Clotet,Bartomeu Massuti,Mariano Provencio,Miguel Angel Molina-Vila,Clara Mayo de las Casa,Mónica Garzón,Peng Cao,Chung-Ying Huang,Javier Martinez-Picado,Rafael Rosell +24 more
TL;DR: In this article, the authors presented a study sponsored by the Spanish Lung Cancer Group (SLCG) and supported by the AstraZeneca Group, which used a Marie Sklodowska-Curie Innovative Training Networks European Grant (ELBA No. 765492), the Spanish Association Against Cancer (AECC) (grant No.PROYE18012ROSE), and the Priority Academic Program Development of Jiangsu Higher Education Institutions (Integration of Chinese and Western Medicine) supported in part the associated translational study.