Judith Dalmau

TL;DR: The authors performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects and found common genetic variants explaining down to 1.3% of the variability in viral load at set point.

TL;DR: This study provides overwhelming confirmation of three associations previously reported in a genome-wide study and shows further independent effects of both common and rare variants in the Major Histocompatibility Complex region (MHC).

TL;DR: It is suggested that early HIV-1 treatment initiation, even when continued for >10 years, is unlikely to lead to viral eradication, but the presence of low viral reservoirs and durable HIV-2 T cell responses may make such patients good candidates for future interventional studies aiming at HIV- 1 eradication and cure.

TL;DR: Safety, tolerability, and immunogenicity results associated with a control of viral replication for a therapeutic vaccine using autologous monocyte-derived dendritic cells (MD-DCs) pulsed with Autologous heat-inactivated whole HIV are reported.

TL;DR: This work characterizes 2 minimally studied clinical patterns of progression to AIDS, whose analysis may inform the understanding of HIV pathogenesis and identify transcriptome differences between rapid progressors and viremic nonprogressors.