M
Monique Murindahabi
Researcher at National University of Rwanda
Publications - 6
Citations - 578
Monique Murindahabi is an academic researcher from National University of Rwanda. The author has contributed to research in topics: Malaria & Artemisinin. The author has an hindex of 5, co-authored 5 publications receiving 203 citations.
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Journal ArticleDOI
Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda.
Aline Uwimana,Eric Legrand,Barbara H. Stokes,Jean-Louis Mangala Ndikumana,Marian Warsame,Noella Umulisa,Daniel Ngamije,Tharcisse Munyaneza,Jean-Baptiste Mazarati,Kaendi Munguti,Pascal Campagne,Alexis Criscuolo,Frédéric Ariey,Monique Murindahabi,Pascal Ringwald,David A. Fidock,Aimable Mbituyumuremyi,Didier Menard +17 more
TL;DR: Identification in Rwanda of mutations in Plasmodium falciparum capable of conferring in vitro resistance to artemisinin, an essential medicine for the treatment of malaria, underscore the crucial need for surveillance in Africa to safeguard efficacy of life-saving therapies.
Journal ArticleDOI
Association of Plasmodium falciparum kelch13 R561H genotypes with delayed parasite clearance in Rwanda: an open-label, single-arm, multicentre, therapeutic efficacy study.
Aline Uwimana,Noella Umulisa,Meera Venkatesan,Samaly S. Svigel,Zhiyong Zhou,Tharcisse Munyaneza,Rafiki M. Habimana,Anicet Rucogoza,Leah F. Moriarty,Ryan Sandford,Emily Piercefield,Ira F. Goldman,Bryan Ezema,Eldin Talundzic,M. Andreína Pacheco,Ananias A. Escalante,Daniel Ngamije,Jean Louis N. Mangala,Michee Kabera,Kaendi Munguti,Monique Murindahabi,William R. Brieger,Clarisse Musanabaganwa,Leon Mutesa,Venkatachalam Udhayakumar,Aimable Mbituyumuremyi,Eric S. Halsey,Naomi W. Lucchi +27 more
TL;DR: In this paper, the efficacy of artemether-lumefantrine and genetic characterisation of Pfkelch13 alleles and their association with treatment outcomes were investigated in three Rwandan sites: Masaka, Rukara, and Bugarama.
Journal ArticleDOI
Efficacy of artemether-lumefantrine versus dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria among children in Rwanda: an open-label, randomized controlled trial.
Aline Uwimana,Michael J Penkunas,Marie Paul Nisingizwe,Marian Warsame,Noella Umulisa,Didier Uyizeye,Clarisse Musanabaganwa,Tharcisse Munyaneza,Edouard Ntagwabira,Dieudonne Hakizimana,Claude Mambo Muvunyi,Claver Kayobotsi,Michee Kabera,Monique Murindahabi,Aimable Mbituyumuremyi +14 more
TL;DR: AL remains efficacious in Rwanda 10 y after its adoption and the probability of new infections occurring among patients in the DHP arm was significantly lower than those in the AL arm.
Posted ContentDOI
Genomic Sequencing of SARS-CoV-2 in Rwanda: evolution and regional dynamics
Yvan Butera,Mukantwari E,Maria Artesi,D’Arc Umuringa J,Áine O'Toole,Hill,Stefan Rooke,Samuel L. Hong,Simon Dellicour,Simon Dellicour,Onesphore Majyambere,Sébastien Bontems,Bouchra Boujemla,Joshua Quick,Paola Cristina Resende,Nicholas J. Loman,Umumararungu E,Kabanda A,Monique Murindahabi,Patrick Tuyisenge,Gashegu M,Rwabihama Jp,Sindayiheba R,Gikic D,Jacob Souopgui,Jacob Souopgui,Wilfred Ndifon,Robert Rutayisire,Swaibu Gatare,Tharcisse Mpunga,Daniel Ngamije,Bours,Andrew Rambaut,Sabin Nsanzimana,Guy Baele,Keith Durkin,Leon Mutesa,Nadine Rujeni +37 more
TL;DR: In this article, the authors present 203 SARS-CoV-2 whole genome sequences analyzed from strains circulating in the country from May 2020 to February 2021, and report a shift in variant distribution towards the newly emerging sub-lineage A.23.1 that is currently dominating.
Journal ArticleDOI
Expanding home-based management of malaria to all age groups in Rwanda: analysis of acceptability and facility-level time-series data.
Aline Uwimana,Michael J Penkunas,Marie Paul Nisingizwe,Didier Uyizeye,Dieudonne Hakizimana,Clarisse Musanabaganwa,Jean Pierre Musabyimana,Alida Ngwije,Innocent Turate,Aimable Mbituyumuremyi,Monique Murindahabi,Jeanine Condo +11 more
TL;DR: The rate of severe malaria increased immediately after implementation within intervention districts relative to controls, potentially because of enhanced case-finding and the rate of increase in severe cases was lower in the intervention districts comparatively, likely due to expedited treatment.