M
Morgan Prust
Researcher at Harvard University
Publications - 22
Citations - 735
Morgan Prust is an academic researcher from Harvard University. The author has contributed to research in topics: Ornithine transcarbamylase deficiency & Medicine. The author has an hindex of 10, co-authored 18 publications receiving 599 citations. Previous affiliations of Morgan Prust include National Institutes of Health & Georgetown University.
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Journal ArticleDOI
GFAP mutations, age at onset, and clinical subtypes in Alexander disease
Morgan Prust,Jichuan Wang,Hiroki Morizono,Albee Messing,Michael Brenner,Erynn Gordon,Thomas R. Hartka,A. Sokohl,Raphael Schiffmann,Heather Gordish-Dressman,Roger L. Albin,H. Amartino,K. Brockman,A. Dinopoulos,M.T. Dotti,D. Fain,R. Fernandez,J. Ferreira,J. Fleming,D. Gill,M. Griebel,H. Heilstedt,Paige Kaplan,D. Lewis,M. Nakagawa,R. C. Pedersen,A. Reddy,Y. Sawaishi,M. Schneider,Elliott H. Sherr,Y. Takiyama,K. Wakabayashi,J. R. Gorospe,Adeline Vanderver +33 more
TL;DR: The proposed revised AxD subtypes, type I and type II, are proposed, based on analysis of statistically defined patient groups, with clear correlations to defined patterns of phenotypic expression.
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Case Definition and Classification of Leukodystrophies and Leukoencephalopathies
Adeline Vanderver,Morgan Prust,Davide Tonduti,Fanny Mochel,Heather M. Hussey,Guy Helman,James Y. Garbern,Florian Eichler,Pierre Labauge,Patrick Aubourg,Diana Rodriguez,Marc C. Patterson,Johan L.K. Van Hove,Johanna L. Schmidt,Nicole I. Wolf,Odile Boespflug-Tanguy,Raphael Schiffmann,Marjo S. van der Knaap +17 more
TL;DR: A case definition of leukodystrophies and classification of heritable white matter disorders will permit more detailed epidemiologic studies of these disorders and help to study the epidemiology and relevance of geneticwhite matter disorders to public health.
Journal ArticleDOI
Chemotherapy, cognitive impairment and hippocampal toxicity
TL;DR: Current preclinical and neuroimaging studies that are providing a potential link between the neurotoxic effects of chemotherapy and hippocampal dysfunction are summarized, highlighting challenges and future directions in this field of investigation.
Journal ArticleDOI
Standard chemoradiation for glioblastoma results in progressive brain volume loss
Morgan Prust,Kourosh Jafari-Khouzani,Jayashree Kalpathy-Cramer,Pavlina Polaskova,Tracy T. Batchelor,Elizabeth R. Gerstner,Jorg Dietrich +6 more
TL;DR: Evidence of significant and progressive treatment-associated structural brain changes in patients with glioblastoma treated with standard chemoradiation is presented and future studies using longitudinal neuropsychological evaluation are needed to characterize the functional consequences of these structural changes.
Journal ArticleDOI
Interactive effects of DAOA (G72) and catechol-O-methyltransferase on neurophysiology in prefrontal cortex
Devon C. Nixon,Morgan Prust,Fabio Sambataro,Hao Yang Tan,Venkata S. Mattay,Daniel R. Weinberger,Joseph H. Callicott +6 more
TL;DR: In this paper, a functional gene × gene interaction between D-amino acid oxidase activator (DAOA) and COMT was detected in the dorsolateral prefrontal cortex (DLPFC) in schizophrenia patients.