F
Fanny Mochel
Researcher at University of Paris
Publications - 176
Citations - 6574
Fanny Mochel is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Triheptanoin. The author has an hindex of 42, co-authored 156 publications receiving 4861 citations. Previous affiliations of Fanny Mochel include University of Rostock & University of Minnesota.
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Journal ArticleDOI
Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
Barry Boland,Wai Haung Yu,Olga Corti,Bertrand Mollereau,Alexandre Henriques,Erwan Bezard,Greg M. Pastores,David C. Rubinsztein,Ralph A. Nixon,Michael R. Duchen,Giovanna R. Mallucci,Guido Kroemer,Beth Levine,Eeva-Liisa Eskelinen,Fanny Mochel,Michael Spedding,Caroline Louis,Olivier R. Martin,Millan Mark +18 more
TL;DR: This article focuses on emerging mechanisms for promoting the clearance of neurotoxic proteins, a strategy that may curtail the onset and slow the progression of NDAs.
Journal ArticleDOI
Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression.
Fanny Mochel,Perrine Charles,François Seguin,Julie Barritault,Christiane Coussieu,Laurence Perin,Yves Le Bouc,Christiane Gervais,Guislaine Carcelain,Anne Vassault,Josué Feingold,Daniel Rabier,Alexandra Durr +12 more
TL;DR: In this paper, a multivariate statistical analysis of plasma components quantified by proton nuclear magnetic resonance (1H NMR) spectroscopy was performed to identify early stages of the Huntington disease.
Journal ArticleDOI
Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia
Rosalinde E.R. Slot,Sietske A.M. Sikkes,Johannes Berkhof,Henry Brodaty,Rachel F. Buckley,Rachel F. Buckley,Enrica Cavedo,Efthimios Dardiotis,Francoise Guillo-Benarous,Harald Hampel,Nicole A. Kochan,Simone Lista,Tobias Luck,Paul Maruff,José Luis Molinuevo,Johannes Kornhuber,Barry Reisberg,Steffi G. Riedel-Heller,Shannon L. Risacher,Susanne Roehr,Perminder S. Sachdev,Nikolaos Scarmeas,Nikolaos Scarmeas,Philip Scheltens,Melanie B. Shulman,Andrew J. Saykin,Sander C.J. Verfaillie,Pieter Jelle Visser,Pieter Jelle Visser,Stephanie J.B. Vos,Michael Wagner,Michael Wagner,Steffen Wolfsgruber,Steffen Wolfsgruber,Frank Jessen,Frank Jessen,Mercè Boada,Peter Paul De Deyn,Roy W. Jones,Giovanni B. Frisoni,L. Spiru,Flavio Nobili,Yvonne Freund-Levi,Hilkka Soininen,Frans R.J. Verhey,Åsa K. Wallin,Jacques Touchon,Marcel G. M. Olde Rikkert,Anne-Sophie Rigaud,Roger Bullock,Magda Tsolaki,Bruno Vellas,Gordon K. Wilcock,Lutz Froelich,Hovagim Bakardjian,Habib Benali,Hugo Bertin,Joel Bonheur,Laurie Boukadida,Nadia Boukerrou,Patrizia A. Chiesa,Olivier Colliot,Bruno Dubois,Marion Dubois,Stéphane Epelbaum,Geoffroy Gagliardi,Remy Genthon,M.-O. Habert,Marion Houot,Aurélie Kas,Foudil Lamari,Marcel Levy,Christiane Metzinger,Fanny Mochel,Francis Nyasse,Catherine Poisson,Marie-Claude Potier,Marie Revillon,Antonio Carlos dos Santos,Katia Andrade,Marine Sole,Mohmed Surtee,Michel Thiebaud de Schotten,Andrea Vergallo,Nadjia Younsi,Wiesje M. van der Flier +85 more
TL;DR: The incidence of Alzheimer's disease and non‐AD dementia and determinants of progression to dementia are assessed and subjective cognitive decline in community‐based and memory clinic settings is assessed.
Journal ArticleDOI
Energy deficit in Huntington disease: Why it matters
Fanny Mochel,Ronald G. Haller +1 more
TL;DR: The clinical, biochemical, and molecular evidence of an energy deficit in HD is reviewed and the mechanisms underlying mitochondrial and related alterations are discussed.
Journal ArticleDOI
Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance.
Fanny Mochel,Melanie A. Knight,Wing Hang Tong,Dena G. Hernandez,Karen Ayyad,Tanja Taivassalo,Peter M. Andersen,Andrew B. Singleton,Tracey A. Rouault,Kenneth H. Fischbeck,Ronald G. Haller,Ronald G. Haller,Ronald G. Haller +12 more
TL;DR: The gene for the iron-sulfur cluster scaffold protein ISCU was identified as a candidate within a region of shared homozygosity among patients with this disease, and a single mutation in ISCU likely strengthens a weak splice acceptor site, with consequent exon retention.