M
Moshe Yaniv
Researcher at Pasteur Institute
Publications - 208
Citations - 23219
Moshe Yaniv is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Transcription factor & Transcription (biology). The author has an hindex of 83, co-authored 207 publications receiving 22714 citations. Previous affiliations of Moshe Yaniv include Centre national de la recherche scientifique.
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A c-jun dominant negative mutant protects sympathetic neurons against programmed cell death
Jonathan Ham,Carol Babij,Jonathan Whitfield,Curt M. Pfarr,Dominique Lallemand,Moshe Yaniv,Lee L. Rubin +6 more
TL;DR: When microinjected into sympathetic neurons, an expression vector for a c-Jun dominant negative mutant protects them against NGF withdrawal-induced death, indicating that AP-1 activity is essential for neuronal cell death.
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Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma
TL;DR: Two distinct nonoverlapping enhancer elements can be defined within the polyoma enhancer region, which provides a 3-fold higher enhancement of the alpha 2-collagen promoter than element B in mouse fibroblasts and in mouse embryonal carcinoma cells.
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A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.
Christian Muchardt,Moshe Yaniv +1 more
TL;DR: It is shown that a counterpart of SNF2/SWI2 also exists in mice and humans, and that the human protein, designated hbrm, is a 180 kDa nuclear factor that can function as a transcriptional activator when fused to a heterologous DNA binding domain.
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CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
Stephen E. Girardin,Régis Tournebize,Maria Mavris,Anne Laure Page,Xiaoxia Li,George R. Stark,John Bertin,Peter S. DiStefano,Moshe Yaniv,Philippe J. Sansonetti,Dana J. Philpott +10 more
TL;DR: It is demonstrated that in addition to the extracellular LPS sensing system mediated by TLRs, mammalian cells also possess a cytoplasmic means of LPS detection via a molecule that is related to plant disease‐resistance proteins.
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JunD Reduces Tumor Angiogenesis by Protecting Cells from Oxidative Stress
Damien Gerald,Edurne Berra,Yves Frapart,Denise A. Chan,Amato J. Giaccia,Daniel Mansuy,Jacques Pouysségur,Moshe Yaniv,Fatima Mechta-Grigoriou +8 more
TL;DR: JunD, a member of the AP-1 family of transcription factors, reduces tumor angiogenesis by limiting Ras-mediated production of ROS and provides new insights into the regulation of PHD activity, allowing immediate reactive adaptation to changes in O2 or iron levels in the cell.