M
Mouna El Bakkali
Researcher at Katholieke Universiteit Leuven
Publications - 3
Citations - 125
Mouna El Bakkali is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 3, co-authored 3 publications receiving 55 citations.
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Journal ArticleDOI
Evaluating totipotency using criteria of increasing stringency.
Eszter Posfai,John P. Schell,John P. Schell,Adrian Janiszewski,Isidora Rovic,Alexander Murray,Brian Bradshaw,Tatsuya Yamakawa,Tine Pardon,Mouna El Bakkali,Irene Talon,Natalie De Geest,Pankaj Kumar,Pankaj Kumar,San Kit To,Sophie Petropoulos,Sophie Petropoulos,Sophie Petropoulos,Andrea Jurisicova,Andrea Jurisicova,Vincent Pasque,Fredrik Lanner,Fredrik Lanner,Janet Rossant +23 more
TL;DR: In this article, the authors define totipotency as the ability of a single cell to give rise to all of the differentiated cell types that build the conceptus, yet how to capture this property in vitro remains incompletely understood.
Journal ArticleDOI
X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels.
Juan Song,Adrian Janiszewski,Natalie De Geest,Lotte Vanheer,Irene Talon,Mouna El Bakkali,Taeho Oh,Vincent Pasque +7 more
TL;DR: It is shown that X-dosage regulates the transcriptome, open chromatin landscape, growth, and pluripotency exit largely independently of global DNA methylation.
Posted ContentDOI
X Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels
Juan Song,Adrian Janiszewski,Natalie De Geest,Lotte Vanheer,Irene Talon,Mouna El Bakkali,Taeho Oh,Vincent Pasque +7 more
TL;DR: The results uncover new insights into X-dosage in pluripotent stem cells, providing principles of how gene dosage modulates the epigenetic and genetic mechanisms regulating cell identity.