Myung Hyun Sohn

TL;DR: These studies establish novel regulatory roles for BRP-39/YKL-40 in the initiation and effector phases of Th2 inflammation and remodeling and suggest that these proteins are therapeutic targets in Th2- and macrophage-mediated disorders.

TL;DR: In this article, the effects of both allergens on the epidermal barrier function as well as on the Epidermal calcium gradient were investigated, and it was shown that when applied on the barrier-disrupted site, increased protease activities in the epIDERmis and delayed barrier recovery and lamellar body secretion in murine skin.

TL;DR: It is suggested that allergens with protease activity can influence the epidermal permeability barrier homeostasis through PAR-2 activation and consequent modulation of the calcium ions in skin.

TL;DR: The findings suggest that resistin may play a negative predictive role in asthma and leptin and adiponectin showed close associations with pulmonary function and may have disease‐modifying effects in children with asthma.

TL;DR: Increased serum thymic stromal lymphopoietin in children with atopic dermatitis is found to increase the risk of developing asthma, according to a study in Pediatr Allergy Immunol 2010.