N
N. de Vries
Researcher at University of Amsterdam
Publications - 99
Citations - 3862
N. de Vries is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Obstructive sleep apnea & Sleep apnea. The author has an hindex of 27, co-authored 98 publications receiving 3548 citations. Previous affiliations of N. de Vries include Royal Hallamshire Hospital & Academic Center for Dentistry Amsterdam.
Papers
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Journal ArticleDOI
An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles.
Anthony G. Wilson,N. de Vries,Flemming Pociot,F. S. Di Giovine,L. B. A. Van Der Putte,Gordon W. Duff +5 more
TL;DR: Frequency analysis of the TNF-alpha polymorphism, using the polymerase chain reaction and single-stranded conformational polymorphism in HLA-typed individuals, reveals a very strong association between the uncommon TNF allele and HLA A1, B8, and DR3 alleles.
Journal ArticleDOI
Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: a prospective cohort study
Wouter H Bos,G.J. Wolbink,Maarten Boers,G J Tijhuis,N. de Vries,I E van der Horst-Bruinsma,Paul P. Tak,R J van de Stadt,C. J. van der Laken,B A C Dijkmans,D. van Schaardenburg +10 more
TL;DR: In patients with arthralgia the presence of ACPA (but not of IgM-RF or SE) predicts arthritis development, and the risk in ACPA-positive patients may be further increased by the concomitant presence of Ig mheumatoid factor or high levels ofACPA.
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Anticipated affective reactions and prevention of AIDS
TL;DR: This study investigated the role of anticipated, post-behavioural, affective reactions to (un)safe sexual behaviours in the context of the theory of planned behaviour (TPB), and showed that anticipated affective reaction predicted behavioural expectations over and above the components of the TPB.
Journal ArticleDOI
A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha
Anthony G. Wilson,C. Gordon,F. S. Di Giovine,N. de Vries,L. B. A. Van De Putte,Paul Emery,Gordon W. Duff +6 more
TL;DR: The data suggest that on the B8‐DR3 haplotype, TNF‐α polymorphism may play a role in SLE susceptibility, but it is not primarily associated with autoantibody production.
Journal ArticleDOI
Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase
M. van de Sande,M J H de Hair,C van der Leij,Paul L. Klarenbeek,Wouter H Bos,Malcolm D. Smith,Mario Maas,N. de Vries,D. van Schaardenburg,Ben A. C. Dijkmans,Danielle M. Gerlag,Paul P. Tak +11 more
TL;DR: Subclinical inflammation of the synovium does not coincide with the appearance of serum autoantibodies during the pre-RA stage, suggesting that a ‘second hit’ is involved and supports the rationale for exploring preventive strategies aimed at interfering with the humoral immune response before synovial inflammation develops.