N
N Joza
Researcher at French Institute of Health and Medical Research
Publications - 7
Citations - 1642
N Joza is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Calreticulin & Autophagy. The author has an hindex of 7, co-authored 7 publications receiving 1504 citations. Previous affiliations of N Joza include University of Paris & Institut Gustave Roussy.
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Journal ArticleDOI
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Michel Obeid,Michel Obeid,Michel Obeid,Theocharis Panaretakis,Theocharis Panaretakis,Theocharis Panaretakis,N Joza,N Joza,N Joza,Roberta Tufi,Roberta Tufi,Roberta Tufi,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,P van Endert,P van Endert,Laurence Zitvogel,Laurence Zitvogel,Guido Kroemer,Guido Kroemer,Guido Kroemer +21 more
TL;DR: Calreticulin exposure is required for the immunogenicity of γ -irradiation and UVC light-induced apoptosis and the ability to reprogram the immune cells for apoptosis.
Journal ArticleDOI
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Theocharis Panaretakis,N Joza,N Joza,N Joza,Nazanine Modjtahedi,Nazanine Modjtahedi,Nazanine Modjtahedi,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,I Vitale,I Vitale,I Vitale,Michael Durchschlag,Gian Maria Fimia,Oliver Kepp,Oliver Kepp,Oliver Kepp,Mauro Piacentini,K-U Froehlich,P van Endert,P van Endert,Laurence Zitvogel,Laurence Zitvogel,Frank Madeo,Guido Kroemer,Guido Kroemer,Guido Kroemer +27 more
TL;DR: Results indicate that tumors that possess an intrinsic defect in the CRT-translocating machinery become resistant to anthracycline chemotherapy due to their incapacity to elicit an anti-cancer immune response.
Journal ArticleDOI
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
Jose Miguel Vicencio,Carla Ortiz,Alfredo Criollo,Aleck W.E. Jones,Oliver Kepp,Oliver Kepp,Oliver Kepp,Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,N Joza,N Joza,I Vitale,I Vitale,I Vitale,Eugenia Morselli,Eugenia Morselli,Eugenia Morselli,M Tailler,M Tailler,M Tailler,Maria Castedo,Maria Castedo,Maria Castedo,Maria Chiara Maiuri,Jordi Molgó,Gyorgy Szabadkai,Sergio Lavandero,Guido Kroemer,Guido Kroemer,Guido Kroemer +30 more
TL;DR: IP3R is identified as a new regulator of the Beclin 1 complex that may bridge signals converging on the ER and initial phagophore formation.
Journal ArticleDOI
No death without life: vital functions of apoptotic effectors
Lorenzo Galluzzi,N Joza,N Joza,Ezgi Tasdemir,Ezgi Tasdemir,Maria Chiara Maiuri,Michael O. Hengartner,John M. Abrams,Nektarios Tavernarakis,Josef M. Penninger,Frank Madeo,Guido Kroemer,Guido Kroemer +12 more
TL;DR: The results corroborate the conjecture that any kind of protein that has previously been specifically implicated in apoptosis might have a phylogenetically conserved apoptosis-unrelated function, most likely as part of an adaptive response to cellular stress.
Journal ArticleDOI
Ecto‐calreticulin in immunogenic chemotherapy
Michel Obeid,Antoine Tesniere,Antoine Tesniere,Antoine Tesniere,Theocharis Panaretakis,Theocharis Panaretakis,Theocharis Panaretakis,Roberta Tufi,Roberta Tufi,Roberta Tufi,N Joza,N Joza,N Joza,Peter van Endert,Peter van Endert,François Ghiringhelli,Lionel Apetoh,Lionel Apetoh,Lionel Apetoh,Nathalie Chaput,Caroline Flament,Evelyn Ullrich,Evelyn Ullrich,Evelyn Ullrich,Stéphane de Botton,Stéphane de Botton,Laurence Zitvogel,Guido Kroemer,Guido Kroemer,Guido Kroemer +29 more
TL;DR: It is discovered that the pre‐apoptotic translocation of intracellular calreticulin to the plasma membrane surface (ecto‐CRT) is critical for the recognition and engulfment of dying tumor cells by dendritic cells.