N
Na Kong
Researcher at Brigham and Women's Hospital
Publications - 79
Citations - 6654
Na Kong is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 25, co-authored 54 publications receiving 3568 citations. Previous affiliations of Na Kong include Hangzhou Normal University & Harvard University.
Papers
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Journal ArticleDOI
Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy
Xianbing Zhu,Xiaoyuan Ji,Na Kong,Na Kong,Yunhan Chen,Morteza Mahmoudi,Xiao-Ding Xu,Li Ding,Wei Tao,Wei Tao,Ting Cai,Yujing Li,Tian Gan,Austin Barrett,Zameer Bharwani,Hongbo Chen,Omid C. Farokhzad +16 more
TL;DR: This is the first systematic experimental report on the nano-bio interaction of 2D nanomaterials in cells and their application for anti-exocytosis-enhanced synergistic cancer therapy.
Journal ArticleDOI
Phosphorus Science-Oriented Design and Synthesis of Multifunctional Nanomaterials for Biomedical Applications
Zhongmin Tang,Na Kong,Jiang Ouyang,Chan Feng,Na Yoon Kim,Xiaoyuan Ji,Cong Wang,Omid C. Farokhzad,Han Zhang,Wei Tao +9 more
TL;DR: The phosphorus science to unify current phosphorus-based nanomaterials is introduced and their synthesis methods are discussed and the representative nanoplatforms utilizing the corresponding properties are highlighted.
Journal ArticleDOI
Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition.
Na Kong,Na Kong,Wei Tao,Xiang Ling,Junqing Wang,Yuling Xiao,Sanjun Shi,Xiaoyuan Ji,Xiaoyuan Ji,Aram Shajii,Silvia Tian Gan,Silvia Tian Gan,Na Yoon Kim,Dan G. Duda,Tian Xie,Omid C. Farokhzad,Omid C. Farokhzad,Jinjun Shi +17 more
TL;DR: Redox-sensitive mRNA nanoparticles help kill tumors by restoring p53 expression by delivering p53-mRNA in nanoparticles and indicate that restoration of tumor suppressors by the synthetic mRNA NP delivery strategy could be combined together with other therapies for potent combinatorial cancer treatment.
Journal ArticleDOI
ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications.
Na Kong,Xiaoyuan Ji,Junqing Wang,Xiu-Na Sun,Guo-Qiao Chen,Taojian Fan,Weiyuan Liang,Han Zhang,Anyong Xie,Omid C. Farokhzad,Wei Tao +10 more
TL;DR: It is revealed that the decreased superoxide dismutase (SOD) activity by lipid peroxides could be an essential mechanism of the selectively higher ROS generation induced by BP-based nanosheets in cancer cells.
Journal ArticleDOI
Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy
Xiaoyuan Ji,Xiaoyuan Ji,Yong Kang,Jiang Ouyang,Yunhan Chen,Dolev Artzi,Xiaobin Zeng,Xiaobin Zeng,Yuling Xiao,Chan Feng,Baowen Qi,Na Yoon Kim,Phei Er Saw,Na Kong,Omid C. Farokhzad,Wei Tao +15 more
TL;DR: An exfoliation approach is provided that combines calcination, n‐butyllithium exchange and intercalation, and liquid exfoliating processes for the high‐yield synthesis of ultrathin BM NSs that allow for multimodal imaging‐guided breast cancer treatment.