N
Na Yin
Researcher at University of Maryland, Baltimore
Publications - 12
Citations - 1452
Na Yin is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Insulitis & Immune system. The author has an hindex of 11, co-authored 12 publications receiving 1356 citations. Previous affiliations of Na Yin include Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
The origin and development of nonlymphoid tissue CD103+ DCs
Florent Ginhoux,Kang Liu,Julie Helft,Milena Bogunovic,Melanie Greter,Daigo Hashimoto,Jeremy Price,Na Yin,Jonathan S. Bromberg,Sergio A. Lira,E. Richard Stanley,Michel C. Nussenzweig,Miriam Merad +12 more
TL;DR: It is shown that two populations of CD11c+MHCII+ cells separated on the basis of CD103 and CD11b expression coexist in most nonlymphoid tissues with the exception of the lamina propria.
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Regulatory T Cells Sequentially Migrate from Inflamed Tissues to Draining Lymph Nodes to Suppress the Alloimmune Response
Nan Zhang,Bernd Schröppel,Girdhari Lal,Claudia Jakubzick,Xia Mao,Dan Chen,Na Yin,Rolf Jessberger,Rolf Jessberger,Jordi Ochando,Jordi Ochando,Yaozhong Ding,Jonathan S. Bromberg +12 more
TL;DR: Results showed that sequential migration from blood to the target tissue and to dLNs is required for Treg cells to differentiate and execute fully their suppressive function.
Journal ArticleDOI
Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival.
TL;DR: Lymphangiogenesis occurs in islet allografts in response to inflammation and plays a key role in the islet inflammation in alloimmunity.
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Distinct Inflammatory Signals Have Physiologically Divergent Effects on Epigenetic Regulation of Foxp3 Expression and Treg Function
Girdhari Lal,Na Yin,Jiangnan Xu,Marvin Lin,S. Schroppel,Yaozhong Ding,Isabelle Marie,David E. Levy,Jonathan S. Bromberg +8 more
TL;DR: In the present study, the Toll‐like receptor 2 (TLR2) ligand peptidoglycan inhibited Foxp3 expression in both natural T Reg (nTreg) and TGFβ‐driven adaptive Treg (aTreg), independent of paracrine Th1, Th2 and Th17 cytokines.
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Islet‐expressed TLR2 and TLR4 sense injury and mediate early graft failure after transplantation
Bernd Krüger,Na Yin,Nan Zhang,Nan Zhang,Anju Yadav,William Coward,Girdhari Lal,Weiping Zang,Peter S. Heeger,Jonathan S. Bromberg,Barbara Murphy,Bernd Schröppel +11 more
TL;DR: Results show that islet graft failure can be initiated by TLR2 and TLR4 signaling and suggest that HMGB1 is one likely early mediator.