Nahed Ismail

TL;DR: Evidence is reported for microbial, antigen-specific activation of NKT cells against Gram-negative, lipopolysaccharide (LPS)-negative alpha-Proteobacteria such as Ehrlichia muris and Sphingomonas capsulata and shows that glycosylceramides are an alternative to LPS for innate recognition of the Gram- negative, LPS-negative bacterial cell wall.

TL;DR: Recent advances in the understanding of ehrlichial diseases related to microbiology, epidemiology, diagnosis, pathogenesis, immunity, and treatment of the 2 prevalent tick-borne diseases found in the United States are reviewed.

TL;DR: This Review summarizes the understanding of the early and late events in pathogenesis and immunity, modulation of the host response to rickettsial infection by the vector, host defence, virulence mechanisms and ricksettsial manipulation of host cells.

TL;DR: Recent advances in the understanding of human ehrlichiosis and anaplasmosis are reviewed, with a focus on Macrophages and neutrophils, the major target cells for Ehrlichia and Anaplasma.

TL;DR: In this paper, the authors compared low and high doses of the highly virulent IOE strain and the less virulent Ehrlichia muris strain that are closely related to E. chaffeensis in C57BL/6 mice.