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Nana-Maria Grüning
Researcher at Max Planck Society
Publications - 15
Citations - 1877
Nana-Maria Grüning is an academic researcher from Max Planck Society. The author has contributed to research in topics: Glycolysis & Pyruvate kinase. The author has an hindex of 11, co-authored 12 publications receiving 1469 citations. Previous affiliations of Nana-Maria Grüning include University of Cambridge & Ruhr University Bochum.
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Journal ArticleDOI
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Anna Stincone,Alessandro Prigione,Thorsten Cramer,Mirjam M.C. Wamelink,Kate Campbell,Eric Cheung,Viridiana Olin-Sandoval,Nana-Maria Grüning,Antje Krüger,Mohammad Tauqeer Alam,Markus A. Keller,Michael Breitenbach,Kevin M. Brindle,Joshua D. Rabinowitz,Markus Ralser,Markus Ralser +15 more
TL;DR: The pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism as discussed by the authors, which shares reactions with the Entner-Doudoroff pathway and the Calvin cycle and divides into an oxidative and non-oxidative branch.
Journal ArticleDOI
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis
Katharina Bluemlein,Nana-Maria Grüning,René G. Feichtinger,Hans Lehrach,Barbara Kofler,Markus Ralser +5 more
TL;DR: The results reveal that an exchange in PKM1 to PKM2 isoform expression during cancer formation is not occurring, nor do these results support conclusions that PKM 2 is specific for proliferating, and PKM 1 for non-proliferating tissue.
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Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells
Nana-Maria Grüning,Mark Rinnerthaler,Katharina Bluemlein,Michael Mülleder,Mirjam M.C. Wamelink,Hans Lehrach,Cornelis Jakobs,Michael Breitenbach,Markus Ralser +8 more
TL;DR: It is discovered that central metabolism is self-adapting to synchronize redox metabolism when respiration is activated, and this autonomous reconfiguration of central carbon metabolism prevents oxidative stress upon shifts between fermentation and respiration.
Journal ArticleDOI
A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4.
Daniela Busse,Philipp Kudella,Nana-Maria Grüning,Günter Gisselmann,Sonja Ständer,Thomas A. Luger,Frank Jacobsen,Lars Steinsträßer,Ralf Paus,Paraskevi Gkogkolou,Markus Böhm,Hanns Hatt,Heike Benecke +12 more
TL;DR: These findings combined with studies on human skin organ cultures strongly indicate that the OR 2AT4 is involved in human keratinocyte re-epithelialization during wound-healing processes.
Journal ArticleDOI
The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response.
Antje Krüger,Nana-Maria Grüning,Mirjam M.C. Wamelink,Martin Kerick,Alexander Kirpy,Dimitri Parkhomchuk,Katharina Bluemlein,Michal-Ruth Schweiger,Aleksey V. Soldatov,Hans Lehrach,Cornelis Jakobs,Markus Ralser +11 more
TL;DR: In this paper, the pentose phosphate pathway (PPP) was found to play a role in the antioxidant response in yeast, and a regulatory signaling function of this metabolic transition in yeast was provided.