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Nancy M. Tofil
Researcher at University of Alabama at Birmingham
Publications - 90
Citations - 1982
Nancy M. Tofil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Cardiopulmonary resuscitation & Medicine. The author has an hindex of 21, co-authored 81 publications receiving 1713 citations. Previous affiliations of Nancy M. Tofil include Georgia Regents University & Medical University of South Carolina.
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Journal ArticleDOI
Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome
Hector R. Wong,Thomas P. Shanley,Bhuvaneswari Sakthivel,Natalie Z. Cvijanovich,Richard Lin,Geoffrey L. Allen,Neal J. Thomas,Allan Doctor,Meena Kalyanaraman,Nancy M. Tofil,Scott Penfil,Marie Monaco,Mary Ann Tagavilla,Kelli Odoms,Katherine E. Dunsmore,Michael R. Barnes,Bruce J. Aronow +16 more
TL;DR: Microarray analyses in children with septic shock within 24 h of intensive care unit admission demonstrate that genome-level alterations of zinc homeostasis may be prevalent in clinical pediatric sepsis.
Journal ArticleDOI
Outcomes of critically ill children requiring continuous renal replacement therapy
TL;DR: For patients with acute kidney injury who require CRRT, the presence of sepsis, MODS, and FO greater than 20% at the time of CRRT initiation are significantly associated with higher mortality.
Journal ArticleDOI
Improving Cardiopulmonary Resuscitation With a CPR Feedback Device and Refresher Simulations (CPR CARES Study) A Randomized Clinical Trial
Adam Cheng,Linda Brown,Jonathan P. Duff,Jennifer Davidson,Frank Overly,Nancy M. Tofil,Dawn Taylor Peterson,Marjorie Lee White,Farhan Bhanji,Ilana Bank,Ronald Gottesman,Mark D. Adler,John Zhong,Vincent Grant,David Grant,Stephanie N. Sudikoff,Kimberly Marohn,Alex Charnovich,Elizabeth A. Hunt,David Kessler,Hubert Wong,Nicola Robertson,Yiqun Lin,Quynh Doan,Jordan Duval-Arnould,Vinay M. Nadkarni +25 more
TL;DR: Using novel and practical technology, JIT training before CPA or real-time VisF during CPA, alone or in combination, improves compliance with American Heart Association guidelines for CPR that are associated with better outcomes.
Journal ArticleDOI
Prevalence of adverse events in pediatric intensive care units in the United States.
Swati Agarwal,David C. Classen,Gitte Y. Larsen,Nancy M. Tofil,Leslie Hayes,Janice E. Sullivan,Stephanie A. Storgion,Barbara J. Coopes,Vicki Craig,Christine Jaderlund,Hema Bisarya,Layla Parast,Paul J. Sharek +12 more
TL;DR: AEs and ADEs occur frequently in the PICU setting and provide areas of focus for evidence-based prevention strategies to decrease the substantial risk to this vulnerable pediatric population.
Journal ArticleDOI
Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock.
Thomas P. Shanley,Natalie Z. Cvijanovich,Richard Lin,Geoffrey L. Allen,Neal J. Thomas,Allan Doctor,Meena Kalyanaraman,Nancy M. Tofil,Scott Penfil,Marie Monaco,Kelli Odoms,Michael R. Barnes,Bhuvaneswari Sakthivel,Bruce J. Aronow,Hector R. Wong +14 more
TL;DR: These data represent the largest reported cohort of patients with septic shock subjected to longitudinal genome- level expression profiling and further advance the genome-level understanding of pediatric septicshock.