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Naoto T. Ueno
Researcher at University of Texas MD Anderson Cancer Center
Publications - 390
Citations - 13778
Naoto T. Ueno is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Breast cancer & Inflammatory breast cancer. The author has an hindex of 59, co-authored 389 publications receiving 11623 citations. Previous affiliations of Naoto T. Ueno include University of Texas Health Science Center at Houston & The Breast Cancer Research Foundation.
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Journal ArticleDOI
A phase Ib study of entinostat plus lapatinib with or without trastuzumab in patients with HER2-positive metastatic breast cancer that progressed during trastuzumab treatment
Bora Lim,Rashmi Krishna Murthy,Jangsoon Lee,S. Jackson,S. Jackson,Toshiaki Iwase,Darren W. Davis,Jie Willey,Jimin Wu,Yu Shen,Debu Tripathy,Ricardo H. Alvarez,Nuhad K. Ibrahim,Abenaa M. Brewster,Carlos H. Barcenas,Powel H. Brown,Sharon H. Giordano,Stacy L. Moulder,Daniel J. Booser,Jeffrey A. Moscow,Richard Piekarz,Vicente Valero,Naoto T. Ueno +22 more
TL;DR: This study identified the MTD of the entinostat, lapatinib, and trastuzumab combination that provided acceptable tolerability and anti-tumour activity in heavily pre-treated patients with HER2+ metastatic breast cancer, supporting a confirmatory trial.
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Initial Staging Impact of Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Locally Advanced Breast Cancer
Naoki Niikura,Jun Liu,Colleen M. Costelloe,Shana L. Palla,John E. Madewell,Naoki Hayashi,Tse Kuan Yu,Yutaka Tokuda,Richard L. Theriault,Gabriel N. Hortobagyi,Naoto T. Ueno +10 more
TL;DR: Among IBC patients, adding PET/CT to staging based on conventional imaging might detect patients with metastases that were not detected by conventional imaging, which is not justified on the basis of these retrospective data.
Journal ArticleDOI
Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors
François Bertucci,Laurys Boudin,Pascal Finetti,Christophe Van Berckelaer,Peter van Dam,Luc Dirix,Patrice Viens,Anthony Gonçalves,Naoto T. Ueno,Steven Van Laere,Daniel Birnbaum,Emilie Mamessier +11 more
TL;DR: In this paper, anti-PD1/PDL1 immune checkpoint inhibitors (ICIs) showed promising results in breast cancer, and exploration of additional actionable immune checkpoints is ongoing.
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Hepatic resection for breast cancer liver metastases: Impact of intrinsic subtypes
Yun Shin Chun,Takashi Mizuno,Jordan M. Cloyd,Min Jin Ha,Kiyohiko Omichi,Ching Wei D. Tzeng,Thomas A. Aloia,Naoto T. Ueno,Henry Mark Kuerer,Carlos H. Barcenas,Jean Nicolas Vauthey +10 more
TL;DR: Surgical resection of BCLM yielded higher OS compared with systemic therapy alone and prolonged PFS among patients with the HER2-enriched subtype, and these findings support the use of surgical therapy in appropriately selected patients, based on intrinsic subtypes.
Journal ArticleDOI
Thrombocytosis as a prognostic factor in inflammatory breast cancer.
Kenichi Harano,Kenichi Harano,Takahiro Kogawa,Jimin Wu,Ying Yuan,Evan N. Cohen,Bora Lim,James M. Reuben,Naoto T. Ueno +8 more
TL;DR: Thrombocytosis was more prevalent in patients with IBC than in those with non-IBC and it was associated with poor prognosis and GRO and TGF-β were associated with thrombocytetosis in IBC.