N
Naoto T. Ueno
Researcher at University of Texas MD Anderson Cancer Center
Publications - 390
Citations - 13778
Naoto T. Ueno is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Breast cancer & Inflammatory breast cancer. The author has an hindex of 59, co-authored 389 publications receiving 11623 citations. Previous affiliations of Naoto T. Ueno include University of Texas Health Science Center at Houston & The Breast Cancer Research Foundation.
Papers
More filters
Journal ArticleDOI
Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer
Jangsoon Lee,Bora Lim,Troy Pearson,Kuicheon Choi,Jon A. Fuson,Chandra Bartholomeusz,Linda J. Paradiso,Thomas Myers,Debu Tripathy,Naoto T. Ueno +9 more
TL;DR: Results indicate that E6201 exhibits anti-tumor efficacy against TNBC in vitro and anti-metastasis efficacy againstTNBC in vivo, and provide a rationale for further clinical development of E 6201 as a MAPK-pathway-targeted therapy for TNBC.
Journal ArticleDOI
Impact of androgen receptor expression in fluoxymesterone-treated estrogen receptor-positive metastatic breast cancer refractory to contemporary hormonal therapy.
Miho Kono,Miho Kono,Takeo Fujii,Genevieve Lyons,Lei Huo,Roland L. Bassett,Yun Gong,Meghan Sri Karuturi,Debasish Tripathy,Naoto T. Ueno +9 more
TL;DR: Fluoxymesterone can be considered for patients whose ER + MBC progresses on contemporary hormonal therapy, regardless of the level of AR expression, despite the type or number of prior systemic treatments.
Journal ArticleDOI
Perspectives on Inflammatory Breast Cancer (IBC) Research, Clinical Management and Community Engagement from the Duke IBC Consortium.
Gayathri R. Devi,Holly Hough,Nadine J. Barrett,Massimo Cristofanilli,Beth Overmoyer,Neil L. Spector,Naoto T. Ueno,Wendy A. Woodward,John P. Kirkpatrick,Benjamin G. Vincent,Kevin P. Williams,Charlotte Finley,Brandi Duff,Valarie Worthy,Shannon J. McCall,Beth A. Hollister,Greg Palmer,Jeremy Force,Kelly Westbrook,Oluwadamilola M. Fayanju,Gita Suneja,Susan Dent,E. Shelley Hwang,Steven R. Patierno,P. Kelly Marcom +24 more
TL;DR: The Duke Consortium for IBC was formed to address the needs of patients in North Carolina and across the Southeastern United States and to translate research into action and improve both awareness and patient care through collaborations with local, national and international IBC programs.
Journal ArticleDOI
The CD151-midkine pathway regulates the immune microenvironment in inflammatory breast cancer.
Steven Hayward,Mariam Gachehiladze,Nahla M Badr,Nahla M Badr,Regina Andrijes,Guerman Molostvov,Liliia Paniushkina,Barbora Sopikova,Zuzana Slobodova,Giorgi Mgebrishvili,Nisha Sharma,Yoshiya Horimoto,Dominic Burg,Graham R. Robertson,Andrew M. Hanby,Fiona Hoar,Daniel Rea,Bedrich L. Eckhardt,Bedrich L. Eckhardt,Naoto T. Ueno,Naoto T. Ueno,Irina Nazarenko,Irina Nazarenko,Heather M. Long,Steven Van Laere,Abeer M Shaaban,Fedor Berditchevski +26 more
TL;DR: It is demonstrated for the first time that changes in the expression of a tetraspanin protein by tumour cells can affect the formation of the immune microenvironment by modulating recruitment of effector cells to cancerous tissues.
Journal ArticleDOI
Comparison of molecular profile in triple-negative inflammatory and non-inflammatory breast cancer not of mesenchymal stem-like subtype.
Yohei Funakoshi,Ying Wang,Takashi Semba,Hiroko Masuda,David R. Hout,Naoto T. Ueno,Xiaoping Wang +6 more
TL;DR: The data suggest that the activity of macrophages might be enhanced in TN-I BC compared with TN-non-IBC, and further clinical and preclinical studies are needed to determine the cross-talk between macrophage and IBC cells.