N
Naresh Vasani
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 11
Citations - 397
Naresh Vasani is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Gene expression profiling & Gene. The author has an hindex of 7, co-authored 11 publications receiving 309 citations. Previous affiliations of Naresh Vasani include United States Environmental Protection Agency & Research Triangle Park.
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Journal ArticleDOI
A photorespiratory bypass increases plant growth and seed yield in biofuel crop Camelina sativa.
Jyoti Dalal,Harry O. Lopez,Naresh Vasani,Zhaohui Hu,Jennifer Swift,Roopa Yalamanchili,Mia Dvora,Xiuli Lin,De-Yu Xie,Rongda Qu,Heike Sederoff +10 more
TL;DR: By reducing photorespiratory losses and increasing photosynthetic CO2 fixation rates, transgenic plants show dramatic increases in seed yield, and the bypass approach may have significant impact on increasing agricultural productivity for C3 crops.
Journal ArticleDOI
Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium
Keiyu Oshida,Keiyu Oshida,Naresh Vasani,Carlton P. Jones,Tanya Moore,Susan D. Hester,Stephen Nesnow,Scott S. Auerbach,David R. Geter,Lauren M. Aleksunes,Russell S. Thomas,Russell S. Thomas,Dawn Applegate,Curtis D. Klaassen,J. Christopher Corton +14 more
TL;DR: It is shown that a CAR biomarker signature coupled with a rank-based similarity method accurately predicts CAR activation, highlighting the promiscuous nature of CAR activation and signaling through activation of other xenobiotic-activated receptors.
Journal ArticleDOI
Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.
Keiyu Oshida,Naresh Vasani,Russell S. Thomas,Dawn Applegate,Mitch Rosen,Barbara D. Abbott,Christopher Lau,Grace L. Guo,Lauren M. Aleksunes,Curtis D. Klaassen,J. Christopher Corton +10 more
TL;DR: Methods useful for future screening of environmental chemicals are developed and identified chemicals that activate or suppress PPARα, and factors including diets and infections that modulate PPAR α activity and would be hypothesized to affect chemical-induced PPARβ activity are identified.
Journal ArticleDOI
Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR).
Keiyu Oshida,Naresh Vasani,Russell S. Thomas,Dawn Applegate,Frank J. Gonzalez,Lauren M. Aleksunes,Curtis D. Klaassen,J. Christopher Corton +7 more
TL;DR: A rank-based test was used to identify factors that activate or suppress AhR in an annotated mouse liver/mouse primary hepatocyte gene expression database of ∼ 1850 comparisons and resulted in a balanced accuracy of 95%.
Journal ArticleDOI
Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event.
TL;DR: Together, these findings identify diverse factors that perturb the hypothalamo-pituitary-liver GH axis and disrupt GH-dependent STAT5b activation in mouse liver.