N
Nathalie Dussault
Researcher at Héma-Québec
Publications - 18
Citations - 372
Nathalie Dussault is an academic researcher from Héma-Québec. The author has contributed to research in topics: Antibody & CD40. The author has an hindex of 9, co-authored 16 publications receiving 246 citations.
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Journal ArticleDOI
Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2.
Romain Gasser,Marc Cloutier,Jérémie Prévost,Corby Fink,Corby Fink,Éric Ducas,Shilei Ding,Nathalie Dussault,Patricia Landry,Tony Tremblay,Audrey Laforce-Lavoie,Antoine Lewin,Antoine Lewin,Guillaume Beaudoin-Bussières,Annemarie Laumaea,Halima Medjahed,Catherine Larochelle,Jonathan Richard,Gregory A. Dekaban,Gregory A. Dekaban,Jimmy D. Dikeakos,Renée Bazin,Andrés Finzi,Andrés Finzi +23 more
TL;DR: In this paper, the authors select plasma from a cohort of convalescent patients with COVID-19 and selectively deplete immunoglobulin A, M or G before testing the remaining neutralizing capacity of the depleted plasma.
Journal ArticleDOI
Characterization of mononuclear cells remaining in the leukoreduction system chambers of apheresis instruments after routine platelet collection: a new source of viable human blood cells
Sonia Néron,Louis Thibault,Nathalie Dussault,Geneviève Côté,Éric Ducas,Nicolas Pineault,Annie Roy +6 more
TL;DR: The residual cell content of these LRS chambers was characterized to determine whether it would be a valuable source of viable human blood cells.
Posted ContentDOI
Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2
Romain Gasser,Marc Cloutier,Jérémie Prévost,Corby Fink,Corby Fink,Éric Ducas,Shilei Ding,Nathalie Dussault,Patricia Landry,Tony Tremblay,Audrey Laforce-Lavoie,Antoine Lewin,Antoine Lewin,Guillaume Beaudoin-Bussières,Annemarie Laumaea,Halima Medjahed,Catherine Larochelle,Jonathan Richard,Gregory A. Dekaban,Gregory A. Dekaban,Jimmy D. Dikeakos,Renée Bazin,Andrés Finzi,Andrés Finzi +23 more
TL;DR: It is found that depletion of immunoglobulin M was associated with the most substantial loss of virus neutralization, followed by immunoglOBulin G, which may help design efficient antibody-based COVID-19 therapies and may also explain the increased susceptibility to SARS-CoV-2 of autoimmune patients receiving therapies that impair the production of IgM.
Journal ArticleDOI
Whole-blood leukoreduction filters are a source for cryopreserved cells for phenotypic and functional investigations on peripheral blood lymphocytes.
TL;DR: Whether these filter‐derived cells could also be used to prepare frozen cell banks to facilitate work organization and open new avenues for their utilization as references in physiological studies and clinical investigations was investigated.
Journal ArticleDOI
B cell proliferation following CD40 stimulation results in the expression and activation of Src protein tyrosine kinase
Sonia Néron,Garnet Suck,Xue-Zhong Ma,Darinka Sakac,Annie Roy,Yulia Katsman,Nathalie Dussault,Claudia Racine,Donald R. Branch +8 more
TL;DR: The finding that SRC expression is inducible and correlates with stimulation by CD154 and the proliferation of the B cells suggests that Src may play a specific role in normal and transformed B cell activation/proliferation pathways mediated primarily through CD40 stimulation.