Nathan C. Gianneschi

TL;DR: Leriche et al. as mentioned in this paper reported the synthesis of a new archaea-inspired tetraether lipid and study the mechanical elastic properties of membranes made from this bolalipid.

TL;DR: In this paper , a liquid crystal (LC) printhead responds to a local chemical stimulus at its aqueous interface, resulting in the ejection of initiator into solution to trigger polymerization.

TL;DR: A novel approach to achieve high loading profiles while ensuring fast and efficient drug penetration in the tumor is provided, co-polymerizing light-sensitive paclitaxel with monomers responsive to tumor-associated enzymes, and assembling the resulting di-block copolymers into spherical micelles that enable therapeutic profiles comparable to that of the free drug.

TL;DR: Using synthetic monolayer-forming lipids with transmembrane tethers, it is revealed that lipid tethering makes membrane permeation an entropically controlled process that helps to limit membrane leakage at elevated temperatures relative to bilayers-forming lipid membranes.

TL;DR: In this article, the authors highlight efforts over the past 10 years at taking advantage of enzymatic reactions to assemble and manipulate complex soft, organic materials on the nanoscale.