N
Nazia Nayeem
Researcher at City University of New York
Publications - 7
Citations - 50
Nazia Nayeem is an academic researcher from City University of New York. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 4 publications receiving 6 citations.
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Journal ArticleDOI
Exploring the Potential of Metallodrugs as Chemotherapeutics for Triple Negative Breast Cancer.
Nazia Nayeem,María Contel +1 more
TL;DR: In this article, the most promising metal-based compounds with potential as chemotherapeutic agents in triple negative breast cancer (TNBC) have been highlighted, and a detailed overview is provided on compounds studied in vivo and those compounds for which some preliminary mechanistic data was obtained.
Journal ArticleDOI
Self-complementary zwitterionic peptides direct nanoparticle assembly and enable enzymatic selection of endocytic pathways
Richard H Huang,Richard H Huang,Nazia Nayeem,Ye He,Ye He,Jorges Morales,Duncan Graham,Rafal Klajn,María Contel,Stephen O'Brien,Rein V. Ulijn +10 more
TL;DR: In this article, the use of zwitterionic tetrapeptide modalities to direct nanoparticle assembly under physiological conditions is reported, where the self-assembly of gold nanoparticles can be activated by enzymatic unveiling of surface-bound ZWT through matrix metalloprotease-9 (MMP-9), which is overexpressed by cancer cells.
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Intracellular Localization Studies of the Luminescent Analogue of an Anticancer Ruthenium Iminophosphorane with High Efficacy in a Triple-Negative Breast Cancer Mouse Model.
Kirill Miachin,Virginia del Solar,Elsy El Khoury,Nazia Nayeem,Anton Khrystenko,Patrícia Appelt,Michelle C. Neary,Daniela Buccella,María Contel +8 more
TL;DR: The potential of ruthenium(II) compounds as an alternative to platinum-based clinical anticancer agents has been unveiled after extensive research for over 2 decades as mentioned in this paper, but its intracellular distribution and ultimate targets remain unknown.
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Encapsulation of Gold-Based Anticancer Agents in Protease-Degradable Peptide Nanofilaments Enhances Their Potency.
Yaron Marciano,Virginia del Solar,Nazia Nayeem,Dhwanit Dave,Ji Hyang Son,María Contel,Rein V. Ulijn +6 more
TL;DR: In this article , the authors investigated the use of peptide nanofilaments as encapsulation moieties for hydrophobic metallodrugs, in order to enhance their bioavailability and consequent activity.
Journal ArticleDOI
Investigation of the Effects and Mechanisms of Anticancer Action of a Ru(II)-Arene Iminophosphorane Compound in Triple Negative Breast Cancer Cells.
TL;DR: Ru-IM (1) as mentioned in this paper is a water-soluble organometallic ruthenium compound, which was shown to be effective in triple negative breast cancer (TNBC) cell lines derived from patients of European and African ancestry.