N
Negar Azami
Researcher at Islamic Azad University
Publications - 6
Citations - 304
Negar Azami is an academic researcher from Islamic Azad University. The author has contributed to research in topics: Cancer & Wnt signaling pathway. The author has an hindex of 5, co-authored 6 publications receiving 82 citations.
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Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy.
Milad Ashrafizadeh,Masoud Delfi,Farid Hashemi,Amirhossein Zabolian,Hossein Saleki,Morteza Bagherian,Negar Azami,Mahdi Vasheghani Farahani,Seyed Omid Sharifzadeh,Soodeh Hamzehlou,Kiavash Hushmandi,Pooyan Makvandi,Ali Zarrabi,Michael R. Hamblin,Rajender S. Varma +14 more
TL;DR: In this paper, the potential of chitosan-based nanoparticles for the delivery of siRNA in cancer therapy is discussed; proliferation, metastasis and chemoresistance are suppressed by siRNA-loaded CS nanoparticles.
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Polychemotherapy with Curcumin and Doxorubicin via Biological Nanoplatforms: Enhancing Antitumor Activity.
Milad Ashrafizadeh,Ali Zarrabi,Farid Hashemi,Amirhossein Zabolian,Hossein Saleki,Morteza Bagherian,Negar Azami,Atefe Kazemzade Bejandi,Kiavash Hushmandi,Hui Li Ang,Pooyan Makvandi,Haroon Khan,Alan Prem Kumar +12 more
TL;DR: Nanoplatforms have been employed for codelivery of curcumin and DOX for promoting the bioavailability and internalization of the aforementioned active compounds in cancer cells and, consequently, enhancing their antitumor activity.
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Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery
Sepideh Mirzaei,Ali Zarrabi,Farid Hashemi,Amirhossein Zabolian,Hossein Saleki,Negar Azami,Soodeh Hamzehlou,Mahdi Vasheghani Farahani,Kiavash Hushmandi,Milad Ashrafizadeh,Haroon Khan,Alan Prem Kumar +11 more
TL;DR: In this article, a review of the signaling networks in which Nrf2 is a key player for protection against DOX adverse effects has been revealed and are discussed in the current review.
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Interplay between SOX9 transcription factor and microRNAs in cancer.
Milad Ashrafizadeh,Ali Zarrabi,Sima Orouei,Amirhossein Zabolian,Hossein Saleki,Negar Azami,Atefe Kazemzade Bejandi,Sepideh Mirzaei,Milad Nemati Janaghard,Kiavash Hushmandi,Noushin Nabavi,Behzad Baradaran,Alan Prem Kumar,Pooyan Makvandi,Saeed Samarghandian,Haroon Khan,Michael R. Hamblin +16 more
TL;DR: In this article, the relationship between miRNAs and SOX9 in different cancers was evaluated to reveal how this interaction can affect proliferation, metastasis and therapy response of cancer cells.
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Resveratrol Modulates Transforming Growth Factor-Beta (TGF-β) Signaling Pathway for Disease Therapy: A New Insight into Its Pharmacological Activities.
Milad Ashrafizadeh,Masoud Najafi,Sima Orouei,Amirhossein Zabolian,Hossein Saleki,Negar Azami,Negin Sharifi,Kiavash Hushmandi,Ali Zarrabi,Kwang Seok Ahn +9 more
TL;DR: Light is shed on the protective effects of Res mediated via the modulation of TGF-β signaling to shed light on the protectiveness of this naturally occurring bioactive compound in the amelioration of diabetic complications.