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Nenad Pavin
Researcher at University of Zagreb
Publications - 70
Citations - 1884
Nenad Pavin is an academic researcher from University of Zagreb. The author has contributed to research in topics: Spindle apparatus & Kinetochore. The author has an hindex of 20, co-authored 67 publications receiving 1620 citations. Previous affiliations of Nenad Pavin include Max Planck Society.
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Journal ArticleDOI
Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters
Liedewij Laan,Nenad Pavin,Nenad Pavin,Julien Husson,Guillaume Romet-Lemonne,Martijn van Duijn,Magdalena Preciado López,Ronald D. Vale,Ronald D. Vale,Frank Jülicher,Samara L. Reck-Peterson,Samara L. Reck-Peterson,Marileen Dogterom,Marileen Dogterom +13 more
TL;DR: It is shown that dynein-mediated pulling forces lead to the reliable centering of microtubule asters in simple confining geometries, and demonstrate the intrinsic ability of cortical microtubules-dynein interactions to regulate micro Tubule dynamics and drive positioning processes in living cells.
Journal ArticleDOI
Self-organization of dynein motors generates meiotic nuclear oscillations.
TL;DR: This work provides the first direct in vivo observation of self-organized dynamic dynein distributions, which, owing to the intrinsic motor properties, generate regular large-scale movements in the cell.
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Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
Janko Kajtez,Anastasia Solomatina,Maja Novak,Bruno Polak,Kruno Vukušić,Jonas Rudiger,Gheorge Cojoc,Ana Milas,Ivana Šumanovac Šestak,Patrik Risteski,Federica Tavano,Anna H. Klemm,Emanuele Roscioli,Emanuele Roscioli,Emanuele Roscioli,Julie P.I. Welburn,Daniela Cimini,Daniela Cimini,Matko Glunčić,Nenad Pavin,Iva M. Tolić +20 more
TL;DR: It is concluded that the bridging fibre, by linking sister k-fibres, withstands the tension between sister kinetochores and enables the spindle to obtain a curved shape.
Journal ArticleDOI
Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes.
TL;DR: It is concluded that sliding of microtubules within the bridging fibers drives pole separation and pushes kinetochore fibers poleward by the friction of passive crosslinks between these fibers.
Journal ArticleDOI
Dynein motion switches from diffusive to directed upon cortical anchoring.
Vaishnavi Ananthanarayanan,Martin H. Schattat,Sven Vogel,Alexander Krull,Nenad Pavin,Nenad Pavin,Iva Marija Tolić-Norrelykke +6 more
TL;DR: It is observed that dyneins on the microtubule move either in a diffusive or directed manner, with the switch from diffusion to directed movement occurring upon binding of dynein to cortical anchors.