Nicholas B. Langhals

TL;DR: An integrated composite electrode consisting of a carbon-fibre core, a poly(p-xylylene)-based thin-film coating that acts as a dielectric barrier and that is functionalized to control intrinsic biological processes, and apoly(thiophene)-based recording pad is developed, found to elicit much reduced chronic reactive tissue responses and enabled single-neuron recording in acute and early chronic experiments in rats.

TL;DR: This study generated and analyzed one of the more comprehensive chronic neural recording datasets to date, and provided a mathematical justification for CAR using Gauss-Markov theorem and therefore help place the application of CAR into a theoretical context.

TL;DR: Results demonstrate that PEDOT coatings enable electrode designs 15 µm in diameter, and demonstrate that chronically implanted control electrodes were unable to record well-isolated unit activity and exhibited a much lower noise floor than controls.

TL;DR: This study investigated localized bleeding resulting from inserting microscale neural probes into the cortex using two-photon microscopy (TPM) and to explore an approach to minimize blood vessel disruption through insertion methods and probe design.

TL;DR: A syringe-implantable electrocardiography (ECG) monitoring system is proposed that successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.