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Nicholas J. Baltes
Researcher at University of Minnesota
Publications - 29
Citations - 4387
Nicholas J. Baltes is an academic researcher from University of Minnesota. The author has contributed to research in topics: CRISPR & Gene targeting. The author has an hindex of 21, co-authored 29 publications receiving 3510 citations.
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Journal ArticleDOI
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
Levi G. Lowder,Dengwei Zhang,Nicholas J. Baltes,Joseph W. Paul,Xu Tang,Xuelian Zheng,Daniel F. Voytas,Tzung-Fu Hsieh,Yong Zhang,Yiping Qi +9 more
TL;DR: A comprehensive molecular toolbox for multifaceted CRISPR/Cas9 applications in plants is developed and implemented, with a full suite of capabilities, including multiplexed gene editing and transcriptional activation or repression of plant endogenous genes.
Journal ArticleDOI
High-frequency, precise modification of the tomato genome
TL;DR: High-frequency, precise modification of the tomato genome was achieved using geminivirus replicons, suggesting that these vectors can overcome the efficiency barrier that has made gene targeting in plants challenging.
Journal ArticleDOI
DNA Replicons for Plant Genome Engineering
TL;DR: The feasibility of using geminivirus replicons to generate plants with a desired DNA sequence modification is demonstrated and the results advocate the use of replicons for plant genome engineering.
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Cryptococcal cell morphology affects host cell interactions and pathogenicity.
Laura H. Okagaki,Anna K. Strain,Judith N. Nielsen,Caroline Charlier,Nicholas J. Baltes,Fabrice Chrétien,Fabrice Chrétien,Joseph Heitman,Françoise Dromer,Kirsten Nielsen +9 more
TL;DR: In this paper, the authors describe a mechanism by which C. neoformans evades host phagocytosis to allow survival of a subset of the population at early stages of infection.
Journal ArticleDOI
Improving cold storage and processing traits in potato through targeted gene knockout.
Benjamin M. Clasen,Thomas Stoddard,Song Luo,Zachary L. Demorest,Jin Li,Frederic Cedrone,Redeat Tibebu,Shawn Davison,Erin E. Ray,Aurelie Daulhac,Andrew Coffman,Ann Yabandith,Adam Retterath,William J. Haun,Nicholas J. Baltes,Luc Mathis,Daniel F. Voytas,Feng Zhang +17 more
TL;DR: The results provide a framework for using TALENs to quickly improve traits in commercially relevant autotetraploid potato lines by knockout VInv within the commercial potato variety, Ranger Russet.