Thomas Stoddard

TL;DR: The ability to create a valuable trait in a single generation through targeted modification of a gene family demonstrates the power of TALENs for genome engineering and crop improvement.

TL;DR: The results provide a framework for using TALENs to quickly improve traits in commercially relevant autotetraploid potato lines by knockout VInv within the commercial potato variety, Ranger Russet.

TL;DR: The methods presented here provide an efficient means for using sequence-specific nucleases to stack quality traits in soybean and comprised oleic acid levels above 80 % and linoleic and linolenic Acid levels below 3 %.

TL;DR: A significant improvement to the standard transcription activator-like effector nuclease architecture is reported by leveraging the partially specific I-TevI catalytic domain to create a new class of monomeric, DNA-cleaving enzymes.

TL;DR: The mutant N. benthamiana lines provide a valuable platform for producing highly potent biopharmaceutical products and the power of TALENs for multiplexed gene editing is demonstrated.