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Nicole L. Rosin
Researcher at University of Calgary
Publications - 34
Citations - 1235
Nicole L. Rosin is an academic researcher from University of Calgary. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 15, co-authored 24 publications receiving 810 citations. Previous affiliations of Nicole L. Rosin include University of British Columbia & Dalhousie University.
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Journal ArticleDOI
Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss.
Wisoo Shin,Nicole L. Rosin,Holly D. Sparks,Sarthak Sinha,Waleed Rahmani,Nilesh Sharma,Matt Workentine,Sepideh Abbasi,Elodie Labit,Jo Anne Stratton,Jeff Biernaskie +10 more
TL;DR: It is shown that HF dermal stem cells (hfDSCs) reconstitute the damaged DP and maintain hair growth, suggesting that hfDSC dysfunction may trigger degeneration of the inductive niche and suggest that progressive dysfunction within the mesenchymal progenitor pool contributes to age-related hair loss.
Journal ArticleDOI
Disruption of Collagen Homeostasis Can Reverse Established Age-Related Myocardial Fibrosis
TL;DR: A novel observation is that BAPN treatment modulated the transforming growth factor-β pathway, collagen synthesis, and the resident macrophage population, which is especially valuable in terms of potential therapeutic targeting of collagen regulation and thereby age-related myocardial fibrosis.
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Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner.
Waleed Rahmani,Yunan Liu,Nicole L. Rosin,Adrienne Kline,Eko Raharjo,Jessica Yoon,Jo Anne Stratton,Sarthak Sinha,Jeff Biernaskie +8 more
TL;DR: A model in which transforming growth factor-β1 and CX3CR1 are critical for recruiting and maintaining the CCR2+CX3 CR1hiLy6CloTNFα+ macrophages critical for stimulating WIHG is proposed.
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Hair follicle dermal stem cells and skin-derived precursor cells: Exciting tools for endogenous and exogenous therapies.
TL;DR: It is contended that dermal stem cells provide an important reservoir of renewable dermal progenitors that may enable development of novel restorative therapies following hair loss, skin injury or disease.
Journal ArticleDOI
Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis
Nicole L. Rosin,Mryanda J. Sopel,Alec Falkenham,Tanya L Myers,Jean-Francois Légaré,Jean-Francois Légaré +5 more
TL;DR: Evidence is provided that myocardial infiltration by fibroblast progenitor cells secondary to AngII and the resultant fibrosis can be prevented by the addition of hydralazine, suggesting that the mechanism of fibrosis is blood pressure dependent.