N
Nicole L. Rosin
Researcher at University of Calgary
Publications - 34
Citations - 1235
Nicole L. Rosin is an academic researcher from University of Calgary. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 15, co-authored 24 publications receiving 810 citations. Previous affiliations of Nicole L. Rosin include University of British Columbia & Dalhousie University.
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Journal ArticleDOI
Macrophages and Associated Ligands in the Aged Injured Nerve: A Defective Dynamic That Contributes to Reduced Axonal Regrowth.
Jo Anne Stratton,Shane E. A. Eaton,Nicole L. Rosin,Sana Jawad,Alexandra Holmes,Grace Yoon,Rajiv Midha,Jeff Biernaskie,Jeff Biernaskie +8 more
TL;DR: Interestingly, impairment in both macrophage accumulation and functional recovery could be overcome by transplanting bone marrow from aged animals into young mice, and the data suggest that age-associated defects in MCP1 signaling could contribute to the regenerative deficits that occur in the aged nervous system.
Journal ArticleDOI
Adult Human Dermal Progenitor Cell Transplantation Modulates the Functional Outcome of Split-Thickness Skin Xenografts
Natacha A. Agabalyan,Holly D. Sparks,Samar Tarraf,Nicole L. Rosin,Katie Anker,Grace Yoon,Lindsay N. Burnett,Duncan Nickerson,Elena S. Di Martino,Vincent Gabriel,Jeff Biernaskie +10 more
TL;DR: C cultured DPCs were transplanted into a full-thickness skin wound in immune-compromised mice and closed with a human STSG, improving both viscoelastic properties of the graft and mitigating pruritus.
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A B1a–natural IgG–neutrophil axis is impaired in viral- and steroid-associated aspergillosis
Nicole Sarden,Sarthak Sinha,Kyle Potts,Erwan Pernet,Carlos Hiroji Hiroki,Mortaza F. Hassanabad,Angela P. Nguyen,Yuefei Lou,Raquel Farias,Brent W. Winston,Amy Bromley,Brendan D. Snarr,Amanda Z. Zucoloto,Graciela Andonegui,Daniel A. Muruve,Braedon McDonald,Donald C. Sheppard,Douglas J. Mahoney,Maziar Divangahi,Nicole L. Rosin,Jeff Biernaskie,Bryan G. Yipp +21 more
TL;DR: Sarden et al. as discussed by the authors investigated three distinct conditions predisposing to lethal aspergillosis, including severe SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection, influenza A viral pneumonia, and systemic corticosteroid use.
Journal ArticleDOI
Comparison of human skin‐ and nerve‐derived Schwann cells reveals many similarities and subtle genomic and functional differences
Tak-Ho Chu,Kabita Baral,Elodie Labit,Nicole L. Rosin,Sarthak Sinha,Daniel Umansky,Saud H Alzahrani,Derrick E. Rancourt,Jeff Biernaskie,Rajiv Midha +9 more
TL;DR: Skin‐derived SCs share near‐identical properties to N‐SCs but with subtle differences that could potentially enhance their therapeutic utility, and single‐cell RNA‐sequencing revealed an overwhelming overlap in gene expression with the exception of HLA genes which were preferentially up‐regulated in Sk‐ SCs.
Journal ArticleDOI
Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis.
Nicole L. Rosin,Alison J. Gareau,Devin Betsch,Alec Falkenham,Mryanda J. Sopel,Timothy D.G. Lee,Jean Francois Legare +6 more
TL;DR: These data suggest that myocardial fibrosis was increased by the addition of exogenous non-specific antibodies in an Fc-mediated manner, which could have substantial impact on the future experimental design of antibody-based therapeutics.