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Nicole Tanenbaum
Researcher at University of Pennsylvania
Publications - 5
Citations - 717
Nicole Tanenbaum is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Antibody & Vaccination. The author has an hindex of 2, co-authored 2 publications receiving 36 citations.
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Journal ArticleDOI
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.
Rishi R. Goel,Mark M Painter,Sokratis A. Apostolidis,Divij Mathew,Wenzhao Meng,Aaron M. Rosenfeld,Kendall A. Lundgreen,Arnold Reynaldi,David S. Khoury,Ajinkya Pattekar,Sigrid Gouma,Leticia Kuri-Cervantes,Philip Hicks,Sarah Dysinger,Amanda Hicks,Harsh Sharma,Sarah Herring,Scott Korte,Amy E. Baxter,Derek A. Oldridge,Josephine R. Giles,Madison E. Weirick,Christopher M McAllister,Moses Awofolaju,Nicole Tanenbaum,Elizabeth M Drapeau,Jeanette Dougherty,Sherea Long,Kurt D'Andrea,Jacob T. Hamilton,Maura McLaughlin,Justine C. Williams,Sharon Adamski,Oliva Kuthuru,Ian Frank,Michael R. Betts,Laura A. Vella,Alba Grifoni,Daniela Weiskopf,Alessandro Sette,Alessandro Sette,Scott E. Hensley,Miles P. Davenport,Paul Bates,Eline T. Luning Prak,Allison R. Greenplate,E. John Wherry,S. Adamski,Z. Alam,M. M. Addison,K. T. Byrne,A. Chandra,H. C. Descamps,Nicholas Han,Y. Kaminskiy,S. C. Kammerman,Justin Kim,A. R. Greenplate,J. T. Hamilton,N. Markosyan,J. Han Noll,D. K. Omran,A. Pattekar,E. Perkey,E. M. Prager,D. Pueschl,A. Rennels,J. B. Shah,J. S. Shilan,N. Wilhausen,A. N. Vanderbeck +70 more
TL;DR: The durability of immune memory after SARS-CoV-2 mRNA vaccination was investigated in this article, where the majority of these cells cross-binding the Alpha, Beta, and Delta variants.
Journal ArticleDOI
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine
Rishi R. Goel,Mark M. Painter,Kendall A. Lundgreen,Sokratis A. Apostolidis,Amy E. Baxter,Josephine R. Giles,Divij Mathew,Ajinkya Pattekar,Arnold Reynaldi,David S. Khoury,Sigrid Gouma,Philip Hicks,Sarah Dysinger,Amanda Hicks,H. Sharma,Sarah Herring,Scott Korte,Wumesh Kc,Derek A. Oldridge,Rachel Erickson,Madison E. Weirick,Christopher M McAllister,M. Awofolaju,Nicole Tanenbaum,Jeanette Dougherty,S. Long,Kurt D'Andrea,J. Hamilton,Maura McLaughlin,Justine C. Williams,Sharon Adamski,Oliva Kuthuru,E. M. Drapeau,Miles P. Davenport,Scott E. Hensley,Paul Bates,Allison R. Greenplate,E. John Wherry +37 more
TL;DR: Greaney et al. as mentioned in this paper examined antibody and memory B cell responses longitudinally for ∼9-10 months after primary 2-dose SARS-CoV-2 mRNA vaccination and 3 months after a 3rd dose.
Posted ContentDOI
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine
Rishi R. Goel,Mark M. Painter,Kendall A. Lundgreen,Sokratis A. Apostolidis,Amy E. Baxter,Josephine R. Giles,Divij Mathew,Ajinkya Pattekar,Arnold Reynaldi,David S. Khoury,Sigrid Gouma,Philip Hicks,Sarah Dysinger,Amanda Hicks,H. Sharma,Sarah Herring,Scott Korte,Wumesh Kc,Derek A. Oldridge,Rachel Erickson,Madison E. Weirick,Christopher M McAllister,M. Awofolaju,Nicole Tanenbaum,Jeanette Dougherty,S. Long,Kurt D'Andrea,J. Hamilton,Maura McLaughlin,Justine C. Williams,Sharon Adamski,Oliva Kuthuru,E. M. Drapeau,Miles P. Davenport,Scott E. Hensley,Paul Bates,Allison R. Greenplate,E. John Wherry +37 more
TL;DR: Examination of antibody and memory B cell responses in a cohort of individuals sampled longitudinally for ∼9-10 months after the primary 2-dose mRNA vaccine series suggests that high levels of circulating antibodies may limit reactivation of immunological memory and constrain further antibody boosting by mRNA vaccines.
Posted ContentDOI
mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern
Rishi R. Goel,Mark M Painter,Sokratis A. Apostolidis,Divij Mathew,Wenzhao Meng,Aaron M. Rosenfeld,Kendall A. Lundgreen,Arnold Reynaldi,David S. Khoury,Ajinkya Pattekar,Sigrid Gouma,Leticia Kuri-Cervantes,Philip Hicks,Sarah Dysinger,Amanda Hicks,Harsh Sharma,Sarah Herring,Scott Korte,Amy E. Baxter,Derek A. Oldridge,Josephine R. Giles,Madison E. Weirick,Christopher M McAllister,Moses Awofolaju,Nicole Tanenbaum,Elizabeth M Drapeau,Jeanette Dougherty,Sherea Long,Jacob T. Hamilton,Maura McLaughlin,Justine C. Williams,Sharon Adamski,Oliva Kuthuru,Ian Frank,Michael R. Betts,Alba Grifoni,Daniela Weiskopf,Alessandro Sette,Scott E. Hensley,Miles P. Davenport,Paul Bates,Eline T. Luning Prak,Allison R. Greenplate,E. John Wherry +43 more
TL;DR: In this article, the authors longitudinally profiled both antibody and cellular immune responses in SARS-CoV-2 naive and recovered individuals from pre-vaccine baseline to 6 months post-mRNA vaccination.
Journal ArticleDOI
Asparagine biosynthesis as a mechanism of increased host lethality induced by Serratia marcescens in simulated microgravity environments
TL;DR: In this article , the authors evaluate the mechanism for increased virulence of the opportunistic gram-negative bacterium, Serratia marcescens, in simulated microgravity, and show that LSMMG increases asparagine uptake and synthesis in S. marceshens and that the increased host lethality induced by LSMMg bacteria grown in rich media can be recapitulated in minimal media by adding only aspartate and glutamine, the substrates of asparaginase biosynthesis.