N
Nike Claessen
Researcher at University of Amsterdam
Publications - 92
Citations - 4057
Nike Claessen is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Kidney & Inflammation. The author has an hindex of 29, co-authored 90 publications receiving 3639 citations.
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Journal ArticleDOI
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
Jaklien C. Leemans,Geurt Stokman,Nike Claessen,Kasper M.A. Rouschop,Gwendoline J. D. Teske,Carsten J. Kirschning,Shizuo Akira,Tom van der Poll,Jan J. Weening,Sandrine Florquin +9 more
TL;DR: Analysis of chimeric mice suggested that TLR2 expressed on renal parenchyma plays a crucial role in the induction of inflammation and injury, implying thatTLR2 blockade could provide a basis for therapeutic strategies to treat or prevent renal ischemic injury.
Journal ArticleDOI
Correction: Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
Alessandra Tammaro,Jesper Kers,Diba Emal,Ingrid Stroo,Gwendoline J. D. Teske,Loes M. Butter,Nike Claessen,Jeffrey Damman,Marc Derive,Gerjan Navis,Sandrine Florquin,Jaklien C. Leemans,Mark C. Dessing +12 more
TL;DR: This research presents a novel probabilistic procedure that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus in the context of infectious disease.
Journal ArticleDOI
TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury
Wilco P. Pulskens,Elena Rampanelli,Gwendoline J. D. Teske,Loes M. Butter,Nike Claessen,Ilse K. Luirink,Tom van der Poll,Sandrine Florquin,Jaklien C. Leemans +8 more
TL;DR: TLR4 attenuates tubular damage but promotes renal fibrosis by modulating the susceptibility of renal cells to TGF-beta, suggesting that TLR4 signaling may be a therapeutic target for the prevention of renal Fibrosis.
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Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.
Lotus M.Th. Sterk,Cecile A. W. Geuijen,José G. Van Den Berg,Nike Claessen,Jan J. Weening,Arnoud Sonnenberg +5 more
TL;DR: The results suggest that the interactions between CD151 and laminin-binding integrins are subject to cell-type-specific regulation.
Journal ArticleDOI
Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway.
Claude Sadis,Gwen J. Teske,Geurt Stokman,Carole Kubjak,Nike Claessen,Fabrice Moore,Patrizia Loi,Bilo Diallo,Luc Barvais,Michel Goldman,Sandrine Florquin,Alain Le Moine +11 more
TL;DR: It is highlighted that nicotine exerts a protective anti-inflammatory effect during kidney I/R through the cholinergic α7nAChR pathway, which could provide an opportunity to overcome the effect of surgicalCholinergic denervation during kidney transplantation.