Nikhil R. Jana

TL;DR: In this article, the individual determination of BeII, MgII or CaII by conventional spectrophotometry and simultaneous determination of Mg II and CaII in mixtures by first-derivative spectrophotsometry are possible at trace levels, using emodin (1,3,8-trihydroxy-6methylanthraquinone) as spectrophoton reagent.

TL;DR: This work shows that nanoformulation of antiamyloidogenic molecule can have better performance as compared to re-regulation of autophagy processes, and this work reports a nanoparticle form of quercetin (nanoquercet in) that shows antiameloidogenic performance at lower quercETin concentration (one micromolar) and inhibits polyglutamine (mutant huntingtin) aggregation in Huntington’s disease cell model.

TL;DR: Hyperbranched polyglycerol dendrimer terminated with anti-amyloidogenic small molecules such as gallate, tyrosine and trehalose and their potential in inhibiting lysozyme/huntingtin protein aggregation under intra/extracellular space are reported.

TL;DR: An approach for transforming AIE active tetraphenylethene (TPE) molecule to galactose-functionalized colloidal nanoparticle that can be used for targeting/labeling of cancer cells and remains intact in the presence of conventional quenchers is reported.

TL;DR: The sensitivity of the SERS detection limit has been improved down to the single molecular level through the formation of hot-particles due to aggregation of core-shell type particles in the presence of NaCl.