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Nitin Gogtay
Researcher at National Institutes of Health
Publications - 110
Citations - 20937
Nitin Gogtay is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Psychosis & Schizophrenia. The author has an hindex of 54, co-authored 108 publications receiving 19141 citations. Previous affiliations of Nitin Gogtay include American Psychological Association & University of Michigan.
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Journal ArticleDOI
Dynamic mapping of human cortical development during childhood through early adulthood
Nitin Gogtay,Jay N. Giedd,Leslie Lusk,Kiralee M. Hayashi,Deanna Greenstein,A. Catherine Vaituzis,Tom F. Nugent,David H. Herman,Liv S. Clasen,Arthur W. Toga,Judith L. Rapoport,Paul M. Thompson +11 more
TL;DR: The dynamic anatomical sequence of human cortical gray matter development between the age of 4-21 years using quantitative four-dimensional maps and time-lapse sequences reveals that higher-order association cortices mature only after lower-order somatosensory and visual cortices are developed.
Journal ArticleDOI
Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia
Tom Walsh,Jon McClellan,Shane McCarthy,Anjené M. Addington,Sarah B. Pierce,Greg M. Cooper,Alexander Nord,Mary Kusenda,Mary Kusenda,Dheeraj Malhotra,Abhishek Bhandari,Sunday M. Stray,Caitlin Rippey,Patricia Roccanova,Vlad Makarov,B. Lakshmi,Robert L. Findling,Linmarie Sikich,Linmarie Sikich,Thomas Stromberg,Barry Merriman,Nitin Gogtay,Philip Butler,Kristen L. Eckstrand,Laila Noory,Peter Gochman,Robert Long,Zugen Chen,Sean Davis,Carl Baker,Evan E. Eichler,Paul S. Meltzer,Stanley F. Nelson,Andrew B. Singleton,Ming K. Lee,Judith L. Rapoport,Mary Claire King,Jonathan Sebat +37 more
TL;DR: The results suggest that multiple, individually rare mutations altering genes in neurodevelopmental pathways contribute to schizophrenia, and disrupted genes disproportionately from signaling networks controlling neurodevelopment, including neuregulin and glutamate pathways.
Journal ArticleDOI
Neurodevelopmental Trajectories of the Human Cerebral Cortex
Philip Shaw,Noor Jehan Kabani,Jason P. Lerch,Kristen L. Eckstrand,Rhoshel K. Lenroot,Nitin Gogtay,Deanna Greenstein,Liv S. Clasen,Alan C. Evans,Judith L. Rapoport,Jay N. Giedd,Steve P. Wise +11 more
TL;DR: By mapping a key characteristic of these development trajectories (the age of attaining peak cortical thickness), this work documents the dynamic, heterochronous maturation of the cerebral cortex through time lapse sequences (“movies”).
Journal ArticleDOI
Intellectual ability and cortical development in children and adolescents
Philip Shaw,Dede Greenstein,Jason P. Lerch,Liv S. Clasen,Rhoshel K. Lenroot,Nitin Gogtay,Alan C. Evans,Judith L. Rapoport,Jay N. Giedd +8 more
TL;DR: This study indicates that the neuroanatomical expression of intelligence in children is dynamic, and finds a marked developmental shift from a predominantly negative correlation between intelligence and cortical thickness in early childhood to a positive correlation in late childhood and beyond.
Journal ArticleDOI
Sexual dimorphism of brain developmental trajectories during childhood and adolescence
Rhoshel K. Lenroot,Nitin Gogtay,Deanna Greenstein,Elizabeth Wells,Gregory L. Wallace,Liv S. Clasen,Jonathan D. Blumenthal,Jason P. Lerch,Alex P. Zijdenbos,Alan C. Evans,Paul M. Thompson,Jay N. Giedd +11 more
TL;DR: This largest longitudinal pediatric neuroimaging study reported to date demonstrates the importance of examining size-by-age trajectories of brain development rather than group averages across broad age ranges when assessing sexual dimorphism and finds robust male/female differences in the shapes of trajectories.