Nora Lang

TL;DR: The engineering of a bioinspired elastic and biocompatible hydrophobic light-activated adhesive (HLAA) that achieves a strong level of adhesion to wet tissue and is not compromised by preexposure to blood is described.

TL;DR: A novel biocompatible and mechanically tunable elastomer, poly(glycerol sebacate urethane) (PGSU), suitable for efficient encapsulation and controlled delivery of bioactive macromolecules and with the potential to be applied to cardiac drug delivery is described.

TL;DR: This approach is applied to develop a robotic technique for closing abnormal communication between the atria of the heart to achieve the efficacy of surgical closure as performed on a stopped, open heart with the reduced risk and trauma of a beating-heart catheter-based procedure.

TL;DR: A multifunctional, catheter-based technology with no implantable rigid components that functions by unfolding an adhesive-loaded elastic patch and deploying a double-balloon design to stabilize and apply pressure to the patch against the tissue defect site has utility in a range of clinical scenarios that warrant minimally invasive and atraumatic repair of hard-to-reach defects.

TL;DR: In selected patients, the combination of a surgical procedure and a percutaneous intervention may help to reduce both operative and interventional risks and enable new treatment options, especially in patients with complex congenital heart defects or complex vascular situations.