O. Hornykiewicz

TL;DR: By measuring dopamine receptors in the putamen and caudate of postmortem brains from Parkinson patients, evidence is reported in support of the theory of dopaminergic supersensitivity in Parkinson's disease.

TL;DR: Treatment strategies that provide more continuous stimulation of dopamine receptors provide reduced motor complications in MPTP monkeys and PD patients and studies raise the possibility that more continuous and physiological delivery of levodopa might reduce the risk of motor complications.

TL;DR: Postmortem data from 12 patients with PD and 10 matched controls compared with five different DA neuronal markers may help in interpretation of in vivo neuroimaging studies in PD in which only one radioligand is routinely employed.

TL;DR: There is sufficient loss of dopamine (DA) in external globus pallidus and the internal globus Pallidum (GPi) as may contribute to the motor manifestations of Parkinson disease (PD).

TL;DR: The data suggest that brain BH4 is decreased substantially in dopamine-responsive dystonia, and dopa-responsive Dystonia can be distinguished from degenerative nigrostriatal dopamine deficiency disorders by the presence of reduced brain neopterin.