O
Ole Vorm
Researcher at Thermo Fisher Scientific
Publications - 25
Citations - 12413
Ole Vorm is an academic researcher from Thermo Fisher Scientific. The author has contributed to research in topics: Mass spectrometry & Sample preparation in mass spectrometry. The author has an hindex of 16, co-authored 25 publications receiving 12000 citations. Previous affiliations of Ole Vorm include Ontario Institute for Cancer Research & European Bioinformatics Institute.
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Journal ArticleDOI
Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels
TL;DR: Silver staining allows a substantial shortening of sample preparation time and may, therefore, be preferable over Coomassie staining, and this work removes a major obstacle to the low-level sequence analysis of proteins separated on polyacrylamide gels.
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Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels
Andrej Shevchenko,O. N. Jensen,Alexandre V. Podtelejnikov,Sagliocco F,Matthias Wilm,Ole Vorm,Peter Mortensen,Boucherie H,Matthias Mann +8 more
TL;DR: This study establishes that mass spectrometry provides the required throughput, the certainty of identification, and the general applicability to serve as the method of choice to connect genome and proteome.
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Improved resolution and very high sensitivity in MALDI TOF of matrix surfaces made by fast evaporation
TL;DR: A simple new sample preparation procedure in which matrix and sample handling are completely decoupled is described, which could be used for protein analysis in particular.
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System-wide Perturbation Analysis with Nearly Complete Coverage of the Yeast Proteome by Single-shot Ultra HPLC Runs on a Bench Top Orbitrap *
Nagarjuna Nagaraj,Nils A. Kulak,Juergen Cox,Nadin Neuhauser,Korbinian Mayr,Ole Hoerning,Ole Vorm,Matthias Mann +7 more
TL;DR: An ultra high pressure liquid chromatography system to a novel bench top Orbitrap mass spectrometer (Q Exactive) with the goal of nearly complete, rapid, and robust analysis of the yeast proteome is proposed.
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A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics
Nicolai Bache,Philipp E. Geyer,Philipp E. Geyer,Dorte B. Bekker-Jensen,Ole Hoerning,Lasse Gaarde Falkenby,Peter V. Treit,Sophia Doll,Igor Paron,Johannes Müller,Florian Meier,Jesper V. Olsen,Ole Vorm,Matthias Mann,Matthias Mann +14 more
TL;DR: The new system - termed Evosep One - analyzes samples in an extremely robust and high throughput manner, without sacrificing in depth proteomics coverage, while maintaining the sensitivity of current nano-flow LC systems.