O
Olga Kifor
Researcher at Brigham and Women's Hospital
Publications - 68
Citations - 11596
Olga Kifor is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Calcium-sensing receptor & Parathyroid chief cell. The author has an hindex of 51, co-authored 68 publications receiving 11241 citations. Previous affiliations of Olga Kifor include Harvard University & University of Picardie Jules Verne.
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Journal ArticleDOI
Cloning, expression, and tissue localization of the calcium-sensing receptor in chicken (Gallus domesticus)
Ruben Diaz,Shelley Hurwitz,Naibedya Chattopadhyay,M. Pines,Y. Yang,Olga Kifor,M. S. Einat,Robert Butters,Steven C. Hebert,Edward M. Brown +9 more
TL;DR: The close conservation of the amino acid sequence of the chicken CaR with its mammalian homologs as well as its similar tissue distribution suggest that the receptor may also play an important role in avian calcium homeostasis.
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The extracellular calcium-sensing receptor is expressed in rat microglia and modulates an outward K+ channel.
Naibedya Chattopadhyay,Chianping Ye,Toru Yamaguchi,Masamichi Nakai,Olga Kifor,Peter M. Vassilev,Robert N. Nishimura,Edward M. Brown +7 more
TL;DR: The data strongly suggest that a functional CaR is expressed in cultured rat microglia, similar to that in parathyroid gland and kidney, which could potentially play an important role(s) in regulating microglial function.
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Abnormal parathyroid cell proliferation precedes biochemical abnormalities in a mouse model of primary hyperparathyroidism.
Sanjay M. Mallya,James J. Gallagher,Yvette K. Wild,Olga Kifor,Jessica Costa-Guda,Kirsten Saucier,Edward M. Brown,Andrew Arnold +7 more
TL;DR: It is observed that decreased expression of the calcium-sensing receptor in the parathyroid glands occurs several months before development of biochemical HPT, suggesting that decreased calcium-Sensing receptor may not be sufficient to cause PTH dysregulation in this animal model of primary HPT.
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Extracellular calcium-sensing receptor (CaR) expression and its potential role in parathyroid hormone-related peptide (PTHrP) secretion in the H-500 rat Leydig cell model of humoral hypercalcemia of malignancy.
TL;DR: In HHM caused by H-500 cells, the CaR could participate in a vicious cycle whereby PTHrP-induced increases in Ca(2+)(o) further stimulate PTHRP release and exacerbate hypercalcemia.
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Identification and functional assay of an extracellular calcium-sensing receptor in Necturus gastric mucosa.
Robert R. Cima,Ivan Cheng,Mary E. Klingensmith,Naibedya Chattopadhyay,Olga Kifor,Steven C. Hebert,Edward M. Brown,David I. Soybel +7 more
TL;DR: The recently cloned extracellular Ca(2+)-sensing receptor (CaR) is present and functioning in Necturus gastric antrum and circuit analysis revealed changes reflected specific decreases in basolateral membrane resistance.