O
Oliver Smithies
Researcher at University of Wisconsin-Madison
Publications - 71
Citations - 25049
Oliver Smithies is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Gene & Globin. The author has an hindex of 41, co-authored 71 publications receiving 24915 citations. Previous affiliations of Oliver Smithies include University of Toronto & Wayne State University.
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Journal ArticleDOI
Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis.
Maeda Nobuyo,David L. Ebert,Thomas M. Doers,Marsha Newman,Judith Hasler-Rapacz,Alan D. Attie,Jan Rapacz,Oliver Smithies +7 more
TL;DR: It is concluded that significant differences in the physiology of LDL particles result from changes outside the putative receptor-binding region, and none of the differences appears to account for the hypercholesterolemic phenotype.
Journal ArticleDOI
Fetal Hemoglobin Variants in Mice
John G. Gilman,Oliver Smithies +1 more
TL;DR: Results of backcrossing the (DBA x C57B1) hybrid to the C 57B1 suggest that the fetal chain locus and the adult β-chain locus are closely linked.
Journal ArticleDOI
Two novel arrangements of the human fetal globin genes: Gγ-Gγ and Aγ-Aγ
TL;DR: These unusual fetal globin gene arrangements could have arisen from point mutations or from gene conversions of limited extent, the boundaries of which have been determined for all three chromosomes.
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Many protein products from a few loci: assignment of human salivary proline-rich proteins to specific loci.
TL;DR: The overall analysis indicates that in many instances several proteins previously considered to be the products of separate loci are actually proteolytic cleavage products of a large precursor specified by one or other of the six genes identified at the DNA level.
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Gene action in the human haptoglobins: I. Dissociation into constituent polypeptide chains
TL;DR: It is concluded that the products hp1Fα, hp1Sα and hp2α are undegraded polypeptide chains with no disulphide bonds in their structures, and that the complex differences in native haptoglobins are the consequences of variations in the hpα polypePTides controlled by the Hp locus.